Microbial Reactions for the Synthesis of Vitamin C (l-Ascorbic Acid)

  • V. Delić
  • D. Šunić
  • D. Vlašić
Part of the Elsevier Applied Biotechnology Series book series (APBISE)


Microbial conversion of several chemical substances deserves special attention, mainly due to its economical and ecological advantages as compared to conventional chemical routes. Industrial production of vitamin C is an example of sophisticated chemical manufacturing involving highly complex and expensive chemical and microbial technology. In this process only one step is mediated by micro-organisms. This review is to provide a complete discussion of results, methods and current ideas of l-ascorbic acid (vitamin C) biosynthesis by micro-organisms, particularly since this field has only rudimentally been covered in the literature (Razumovskaya, 1962; Kulhanek, 1970; Crawford & Crawford, 1980).


Microbial Production European Patent Acetic Acid Bacterium Japan Patent Hexuronic Acid 
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Copyright information

© Elsevier Science Publishers Ltd 1989

Authors and Affiliations

  • V. Delić
    • 1
  • D. Šunić
    • 1
  • D. Vlašić
    • 1
  1. 1.Chemical, Food And Cosmetic Industry, Research InstitutePLIVA PharmaceuticalZagrebYugoslavia

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