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Ultrafiltration and Hemofiltration: Practical Applications

  • Conrad A. Baldamus
  • Manfred Pollok

Abstract

The modern era of hemofiltration began with its clinical application in 1976. Before that, Henderson and colleagues (1, 2), Quellhorst and associates (3–6), and Dorson and Markowitz (7, 8) had contributed to the physical principles (9, 10), reported first clinical results (6) and recycled purified ultrafiltrate (11). This work would have been inconceivable without the membrane technology developed by industrial firms, such as Amicon (9) and Sartorius (3). The dialysis community became curious about the new technology when in 1976 the first workshop on hemofiltration was held in Braunlage (Table 1) initiated by the German group of Quellhorst. At this meeting a variety of clinical benefits were reported (12) including improvement of anemia, neuropathy, lipid metabolism, hypertension control, hyperparathyroidism and symptomatology. This impressive list of advantages recommended hemofiltration as the panacea in end-stage renal disease (ESRD) treatment. Thereafter industry developed automatic balancing equipment (13) on a volumetric or gravimetric basis and different membranes for flat sheet or hollow fiber filters; simultaneously the complicated dynamics of fluid and solute transfer (9, 10) were elucidated.

Keywords

Carpal Tunnel Syndrome Hollow Fiber Mean Arterial Blood Pressure Total Peripheral Resistance Continuous Ambulatory Peritoneal Dialysis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Kluwer Academic Publishers 1989

Authors and Affiliations

  • Conrad A. Baldamus
  • Manfred Pollok

There are no affiliations available

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