New Approaches to Intermittent Peritoneal Dialysis Therapies

  • Zbylut J. Twardowski


In 1923, Ganter [1] reported what probably was the first clinical application of peritoneal dialysis. He infused 1.5 l of normal saline in one patient and 3 l in another. Only single exchanges were used. In later years, two techniques of peritoneal dialysis were developed: a) continuous flow and b) intermittent flow. In continuous flow peritoneal dialysis, dialysis solution was infused through a trocar or tubing into the upper abdomen and drained simultaneously through another trocar or tubing introduced into the lower abdomen. This technique dominated in the 1920s and 1930s [2–5]. In intermittent flow peritoneal dialysis only a single trocar or rubber catheter was used. Fluid was infused into the peritoneal cavity, equilibrated for a short time, and drained through the same trocar or catheter. This method was studied in laboratory animals in the early 1930s [6, 7]. The first intermittent flow peritoneal dialysis in a patient was probably performed by Rhoads on June 17, 1936 [8]. Abbott and Shea [9] made further improvements in the intermittent flow technique.


Peritoneal Dialysis Continuous Ambulatory Peritoneal Dialysis Residual Renal Function Dialysis Solution Continuous Ambulatory Peritoneal Dialysis Patient 
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© Kluwer Academic Publishers 1989

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  • Zbylut J. Twardowski

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