Systolic time intervals: basis and application

  • David H. Spodick
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 92)


Systole, like diastole, can be divided into physiologically (and ultimately clinically) significant intervals. They have been explicitly or intuitively measured for more than a century, but the modern application of systolic time intervals (STI) results from the work of Blumberger; all subsequent work has been variations on the remarkable range of his physiologic, clinical and pharmacologic investigations, though perhaps with more sophisticated statistical analyses. More recent interest in STI was stimulated by the many contributions of Weissler.


Mitral Regurgitation Pericardial Effusion Heart Sound Aortic Valve Disease Systolic Time Interval 
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Copyright information

© Kluwer Academic Publishers 1989

Authors and Affiliations

  • David H. Spodick
    • 1
    • 2
  1. 1.Clinical CardiologySaint Vincent Hospital; University of Mass. Medical SchoolUSA
  2. 2.Tufts University School of Medicine; Boston University School of MedicineUSA

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