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Immunization against leprosy

  • Chapter
Recent Developments in Prophylactic Immunization

Part of the book series: Immunology and Medicine ((IMME,volume 12))

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Abstract

In 1978 the WHO Committee on the Immunology of Leprosy, IMMLEP, defined the development of a prophylactic vaccine against leprosy as an objective of high priority. Ten years later, trials are under way of the approaches they identified, namely, vaccines based on antigenically similar cultivatable mycobacteria, killed Mycobacterium leprae, or of a mixture of killed M. leprae with BCG. This chapter will discuss the rationale for such vaccines, together with the possibility of a second-generation vaccine, based on protective antigens produced either by molecular biology or as synthetic peptides.

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Authors
  1. H. M. Dockrell
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  2. K. P. W. J. McAdam
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Editors and Affiliations

  1. Department of Medical Microbiology, London School of Hygiene and Tropical Medicine, University of London, London, UK

    A. J. Zuckerman

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Dockrell, H.M., McAdam, K.P.W.J. (1989). Immunization against leprosy. In: Zuckerman, A.J. (eds) Recent Developments in Prophylactic Immunization. Immunology and Medicine, vol 12. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1067-6_4

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  • DOI: https://doi.org/10.1007/978-94-009-1067-6_4

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