Molecular Anatomy of the Chicken Major Histocompatibilty B Complex

  • Charles Auffray
Part of the Current Topics in Veterinary Medicine and Animal Science book series (CTVM, volume 52)

Abstract

Resistance or susceptibility to the development of tumors induced by Marek’s disease virus or Rous sarcoma virus in chickens is controlled by the major histocompatibility B complex. The recent cloning of chicken B complex B-L (class II), B-F (class I) and B-G (class IV) genes has provided new tools for molecular genotyping which should complement available serological and cellular assays and help identifying the B complex genes involved in disease control. The identification of 22 genes in the 320 kb of the B complex which have been cloned make it a prime target for a large scale collaborative sequencing project.

Keywords

RFLP Marker Rous Sarcoma Virus Cosmid Clone Molecular Genotyping Congenic Line 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© ECSC,EAEC,Brussels and Luxembourg 1989

Authors and Affiliations

  • Charles Auffray
    • 1
  1. 1.Institut d’Embryologie du CNRS et du Collège de France 49bisNogent s/MarneFrance

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