Hemodynamics in patients with overweight and hypertension

  • Efrain Reisin
  • Edward D. Frohlich
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 98)

Abstract

Several epidemiological studies, cross-sectional [1–3] and longitudinal [1, 4–6], have shown that obesity and hypertension are two directly related pathological disorders at any age [1, 7], and the overweight condition is a predicting and predisposing factor for future development of elevated systolic and diastolic pressures [4–6]. More recent studies, however, have concluded that in determining the risk profile of obese subjects, assessment of body fat distribution is important [8–11]. Thus, considerably evidence suggests that fat distribution is a relatively constant characteristic of human beings, even after major weight changes [8, 9]. By a variety of techniques, such as skinfold thickness measurements [10], circumference measurements [10–12], and computed tomography [13], estimates of fat distribution in different body regions support the concept that an increased waist-hip circumference ratio (upper-body obesity or hypertrophic obesity) shows a preponderance of fat in the abdominal region. This specific type of obesity, in contrast to subjects having low waist-hip circumference ratios (lower-body obesity or hyperplastic obesity), is associated with increased risk of hypertension, impaired glucose tolerance, and hyperinsulinemia [14–17]. This finding is true across race and gender groups and is independent of age [16, 17].

Keywords

Weight Reduction Caloric Restriction Plasma Renin Activity Sodium Intake Total Peripheral Resistance 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Kluwer Academic Publishers 1989

Authors and Affiliations

  • Efrain Reisin
  • Edward D. Frohlich

There are no affiliations available

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