Cyclopropyl Group Containing Amino Acids From α-Chlorocyclopropylidenacetates

  • Norbert Krass
  • Ludger Wessjohann
  • Dahai Yu
  • Armin de Meijere
Part of the NATO ASI Series book series (ASIC, volume 273)

Abstract

Cyclopropane amino acids have attracted the attention of synthetically and biologically oriented chemists throughout the last decade. Most efforts have been directed towards 1-aminocyclopropane carboxyclic acid (ACC), the natural precursor of the phytohormone ethylene,1 and its derivatives. Other natural cyclopropane amino acids as well as artificial ones were used as enzyme inhibitors for receptor and metabolism studies.2 We report here a new synthetic approach to a wide variety of cyclopropyl-substituted amino acids including the natural products cleonin (1) (1-hydroxycyclopropyl-glycin)3 and 1-methylcyclopropyl- glycin (2).4

Keywords

Natural Precursor CYCLOPROPYL Group Acetate Enolate Potassium Phthalimide Phytohormone Ethylene 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic Publishers 1989

Authors and Affiliations

  • Norbert Krass
    • 1
  • Ludger Wessjohann
    • 1
  • Dahai Yu
    • 1
  • Armin de Meijere
    • 1
  1. 1.Institut für Organische Chemieder Universität HamburgHamburg 12West-Germany

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