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Photolabeling Reagent Design

  • Ole Buchardt
  • Ulla Henriksen
  • Troels Koch
  • Peter E. Nielsen
Part of the NATO ASI Series book series (ASIC, volume 272)

Abstract

Photolabeling reagents are composed of some or all of the following ligands: Photoprobes, thermal probes, labels, linkers, and cleavable sites. The design and function of such ligands are discussed on the basis of our own attempts to design and test novel ligands and reagents. Novel ligands include diazocyclopentadienylcarbonyloxy photoprobes, biotinyl labels and selenium containing linkers which can be cleaved by very mild oxidation.

Keywords

Quantum Yield Thermal Probe Radioactive Label Diazo Compound Mild Oxidation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic Publishers 1989

Authors and Affiliations

  • Ole Buchardt
    • 1
  • Ulla Henriksen
    • 1
  • Troels Koch
    • 1
  • Peter E. Nielsen
    • 2
  1. 1.Research Center for Medical Biotechnology, The H. C. Ørsted InstituteUniversity of CopenhagenCopenhagen ØDenmark
  2. 2.Department of Biochemistry BThe Panum InstituteCopenhagen NDenmark

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