Effects of Anesthetics on Pulmonary Gas Exchange

  • Bryan E. Marshall
Part of the Developments in Critical Care Medicine and Anaesthesiology book series (DCCA, volume 19)


While much has been written about problems of gas exchange during anesthesia, not all the questions have been resolved. This complexity is well illustrated in the current controversy concerning the use of inhalational agents for the maintenance of anesthesia during one-lung ventilation and thoracic surgery. Most authors have suggested caution in the use of inhalational agents in these circumstances because inhibition of hypoxic pulmonary vasoconstriction (HPV) may contribute to hypoxemia (6,21,29); others have concluded that the inhibition does not occur or is unimportant in practice (5,13). The data on which these contrasting conclusions are based will be reviewed in an attempt to reconcile these viewpoints.


Minimum Alveolar Concentration Hypoxic Pulmonary Vasoconstriction Arterial Oxygen Tension Inhalational Agent Dependent Lung 
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Copyright information

© Kluwer Academic Publishers 1989

Authors and Affiliations

  • Bryan E. Marshall
    • 1
  1. 1.Department of AnesthesiaUniversity of Pennsylvania School of MedicinePhiladelphiaUSA

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