Neurobehavioural Effects of Foetal Lead Exposure: The First Year of Life

  • K. N. Dietrich
  • K. M. Krafft
  • M. Bier
  • O. Berger
  • P. A. Succop
  • R. L. Bornschein


Evidence from several recent prospective and retrospective studies indicates that lead may be psychoteratogenic at relatively low levels of foetal exposure. In the present interim study, lead measured in whole blood during the prenatal (maternal blood lead) and neonatal periods was found to be inversely related to a complex of sensorimotor developmental indices at 6 and 12 months. Prenatal blood lead was also related to lower birth weight, which in turn was related to poorer sensorimotor performance in infants during the first year. These adverse effects were observed at levels of lead exposure common in pregnant women in the United States, Europe, and other developed areas.


Lead Exposure Prenatal Exposure Blood Lead Level Blood Lead Concentration White Infant 
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Copyright information

© ECSC-EEC-EAEC, Brussels — Luxembourg; EPA, USA 1989

Authors and Affiliations

  • K. N. Dietrich
  • K. M. Krafft
  • M. Bier
  • O. Berger
  • P. A. Succop
  • R. L. Bornschein

There are no affiliations available

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