Separation of Ruthenium and Molybdenum by Cation Exchange Chromatography on Ag 50W-X4 in a Nitric Acid-Ethylenediamine Mixture
The 99Mo-99Tc-generator is widely used in nuclear medicine. 99Mo can be obtained from the fission of 235U in a nuclear reactor. 103Ru is one of the numerous fission products to be separated from 99Mo. 103Ru can easily be separated from 99Mo by cation exchange chromatography on AG 50W-X4 in a nitric acid- ethylenediamine mixture. Ruthenium is sorted as a positively charged ruthenium-ethylenediamine complex from a mixture containing 0,10M nitric acid and 0,01M ethylenediamine or 1,0M nitric acid and 0,10M ethylenediamine. Molybdenum passes through the resin column and can be separated from the ethylenediamine by ion exchange chromatography on aluminium oxide or manganese dioxide.
KeywordsManganese Dioxide Elution Curve Sodium Molybdate Hydrobromic Acid Cation Exchange Chromatography
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- 2.Milenkovic, S. M., Vucina, J. L., Jacimovic, Lj. M., Karanfilov, E.S. and Memodivic, T. V., Universal 99mTc generator for human use. Isotopenpraxis, 1982, 18, 85–87Google Scholar
- 3.Brown, J. L. and Harris, O. A. Technetium-99m generator. Ger. Offen. 2,242,395 (Cl. C Olg), 15 Mar 1973, US Appl. 177,249, 2 Sep 1971, 25 ppGoogle Scholar
- 7.Fourie, P. J. Progress in the development of technetium-99m technology in South Africa. In Technetium-99m Technology, ed. M. Beyers, Third Congress of the S A Society of Nuclear Medicine, Bloemfontein, 14–17 August 1988, pp 3–10Google Scholar
- 8.Ejaz, M. Separation of molybdenum (VI) from uranium (VI) and fission products. Radiochimica Acta, 1975, 22, 51–52Google Scholar
- 9.Salacz, J. Reprocessing of irradiated uranium-235 for the production of 99Mo, 131I, 133Xe radioisotopes. Revue IRE Tijdschrift, 1985, 9, 22–28Google Scholar
- 14.Sameh, A. Production of molybdenum-99. PROCEEDINGS International Symposium on Isotope Applications, Taipei, Taiwan, Republic of China, December 4–5, 1986, 291–303.Google Scholar