Abstract
Diagnostic approach to coronary artery disease patients primarily involves the internist Anamnesis, physical examination and evaluation of risk factors enable the internist to assess a priori the pretest probability of coronary artery disease (CAD). Therefore a diagnostic iter will be started employing a sequence of independent tests. The goal of the sequence is to obtain a growing acquisition of knowledge in order to place the patient into a sufficiently low or high disease probability category.This approach is based on the sequential bayesian analysis, the statistical law of conditional probability, which states that the posttest probability can not be directly assessed only by the test result but it is influenced by the prevalence of disease, namely pretest probability. This clinical procedure is effective in the vast majority of patients, and yet some limiting factors to a strict bayesian approach have to be considered. Sometimes the tests employed are not independent, the test results are not absolutely negative or positive and prominently we have not an adequate gold standard representing an ideal marker of myocardial ischemia.
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© 1990 Kluwer Academic Publishers
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Sangiorgi, M., De Nardo, D. (1990). Diagnosis and evaluation of ischemic heart disease. In: Descovich, G., Gaddi, A., Magri, G., Lenzi, S. (eds) Atherosclerosis and Cardiovascular Disease. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0731-7_74
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DOI: https://doi.org/10.1007/978-94-009-0731-7_74
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