The effects of monounsaturated fatty acids on serum lipoprotien levels in healthy adult volunteers
The effects of monounsaturated fatty acids on serum lipids were studied in healthy women and men in two separate well-controlled dietary studies. In the first study it was shown that replacement of saturated fatty acids by either monounsaturated fatty acids or carbohydrates caused similar changes in serum total and LDL cholesterol levels. The HDL cholesterol level, however, was significantly lower on the diet high in carbohydrates. In the second study it was found that replacement of saturated fatty acids by a mixture of monounsaturated and polyunsaturated fatty acids caused similar serum lipid levels as replacement with polyunsaturated fatty acids alone.
It is concluded that replacement of saturated fats by oils rich in monounsaturated fatty acids might be an attractive option for optimizing serum lipid levels.
KeywordsPolyunsaturated Fatty Acid Saturated Fatty Acid Monounsaturated Fatty Acid Clinic Coronary Primary Prevention Trial Research Clinic Coronary Primary Prevention
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- 3.Keys A, ed. Coronary Heart Disease in Seven Countries. Circulation 1970;41:suppl 1.Google Scholar
- 4.The Lipids Research Clinics Coronary Primary Prevention Trial Results. II. Therelationship of reduction in incidence of coronary heart disease to cholesterol lowering. JAMA 1984; 251: 365–374.Google Scholar
- 8.Mensink RP, Katan MB. Effect of a diet enriched with monounsaturated or polyunsaturated fatty acids on levels of low-density and high-density cholesterol in healthy women and men. N Engl J Med; 321: 436–441.Google Scholar
- 10.Snedecor GW, Cochran WG. Statistical methods. 7th ed. Ames: Iowa State University Press, 1980.Google Scholar
- 12.West CE, Sullivan DR, Katan, MB, Halferkamps IL, van der Torre HW. Boys from populations with high carbohydrate intake have higher fasting triglycerides than boys from populations with high fat intake. Am J Epidemiol, in press.Google Scholar
- 15.Beynen AC, Katan MB. In: Vergroesen AJ, Crawford MA, eds. The role of fats in human nutrition. Impact of dietary cholesterol and fatty acids on serum lipids and lipoproteins in man. London: Academic Press Limited, 1989: 238–54Google Scholar