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Cholesterol-CHD connection: evidence for the benefit of lipoprotein modification

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Abstract

Several clinical studies using lipid-lowering diets or agents have shown that lowering total cholesterol and low density lipoprotein (LDL) -cholesterol can help prevent coronary heart disease (CHD) death and non-fatal myocardial infarction [1,2]. In addition, two recent studies have shown that elevated levels of high density lipoprotein (HDL) -cholesterol also prevent CHD events [3,4].

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References

  1. Lipid Research Clinics Program: The Lipid Research Clinics1 Coronary Primary Prevention Trial (CPPT) Results. I and II. JAMA 1984; 251: 351–374.

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  2. Canner PL, Berge KG, Wenger NK, et al: Fifteen year mortality in Coronary Drug Project patients: long-term benefit with niacin. J Am Coll Cardiol 1986; 8: 1245–1255.

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  5. Hjermann I, Holme I, Leren P: Oslo Study Diet and Antismoking Trial. Results after 102 months. Am J of Med 1986; 80 (2A): 7–11.

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Author information

Authors and Affiliations

  1. Department of Medicine, Internal Medicine Service, The Methodist Hospital, 6565 Fannin, M.S. A-601, Houston, TX, 77030, USA

    A. M. Gotto Jr. (Chief)

Authors
  1. A. M. Gotto Jr.
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Editor information

Editors and Affiliations

  1. Clinica Medica Generale e Terapia Medica I, Policlinico S. Orsola, via Massarenti, 9, Bologna, 40138, Italy

    Giancarlo Descovich , Antonio Gaddi , Gianluigi Magri  & Sergio Lenzi , ,  & 

  2. Department of Gerontology and Atherosclerosis Centre, University of Bologna, via Massarenti 9, Bologna, 40138, Italy

    Giancarlo Descovich  & Antonio Gaddi  & 

  3. Department of Geriatrics and Lipid Clinic, University of Bologna, Bologna, 40138, Italy

    Gianluigi Magri

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© 1990 Kluwer Academic Publishers

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Gotto, A.M. (1990). Cholesterol-CHD connection: evidence for the benefit of lipoprotein modification. In: Descovich, G., Gaddi, A., Magri, G., Lenzi, S. (eds) Atherosclerosis and Cardiovascular Disease. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0731-7_1

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  • DOI: https://doi.org/10.1007/978-94-009-0731-7_1

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6814-7

  • Online ISBN: 978-94-009-0731-7

  • eBook Packages: Springer Book Archive

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