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Amyloid heart disease

  • C. M. Oakley
Part of the Current Status of Clinical Cardiology book series (CSOCC, volume 1)

Abstract

Virchow gave amyloid its name because the material gives a colour reaction to iodine which is similar though not identical to that given by starch. Amyloidosis is a disorder of protein metabolism and amyloid is an abnormal eosinophilic fibrillar protein which is laid down inter-cellularly. The characteristic fibrillar deposits can be formed from a number of different precursor proteins which in all cases are bound to a normal non-fibrillar glycoprotein, amyloid P component. Different forms of amyloid fibrils are identified by distinctive light and electron microscopic appearances1,2. Amyloid can be deposited in almost any organ of the body and occurs in many characteristically distinct forms in different clinical conditions and by several different pathogenetic mechanisms.

Keywords

Familial Mediterranean Fever Carpal Tunnel Syndrome Hypertrophic Cardiomyopathy Pericardial Effusion Amyloid Deposit 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic Publishers 1990

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  • C. M. Oakley

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