Normal Histology and Inflammatory Conditions of the Nose and Paranasal Sinuses

  • L. Michaels
Part of the Current Histopathology book series (CUHI, volume 16)


The vestibule, the anterior chamber of the nasal cavity, is lined by an internal extension of the integument of the external nose, including a keratinizing stratified squamous epithelial surface and an underlying dermis containing hair follicles, sebaceous and sweat glands. The degree of posterior extension of the vestibule varies with physiological conditions, races and individuals. The average depth is between 1 and 2 cm from the external rim of the nares. As the mucocutaneous junction (limen nasi) representing the anterior limits of the inner nasal cavity proper is approached, there is a gradual diminution and disappearance of the adnexa.


Nasal Cavity Paranasal Sinus Nasal Mucosa Nasal Polyp Olfactory Epithelium 
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  1. 1.
    Anson, B. J. (1966). Morris’ Human Anatomy. A Complete Systemic Treatise. 12th Edn. (New York: McGraw-Hill).Google Scholar
  2. 2.
    Jafek, B.W. (1983). Ultrastructure of human nasal mucosa. Laryngoscope, 93, 1576–1599.Google Scholar
  3. 3.
    Matulionis, D. H., Breipohl, W. and Bhatnagar, K. P. (1982). Degeneration and regeneration of olfactory epithelium in the mouse. A scanning electron microscopic study. Ann. Otoi. Rhinol. Laryngol., 91 (Suppl. 89), 1–12.Google Scholar
  4. 4.
    Reyes, E. (1946). Rhinoscleroma; observations based on study of 200 cases. Arch. Dermatol. 54, 531–537.CrossRefGoogle Scholar
  5. 5.
    Lindsay, J. R. and Perlman, H. B. (1951). Sarcoidosis of upper respiratory tract. Ann. Otol. Rhinol. Laryngol., 60, 549–566.PubMedGoogle Scholar
  6. 6.
    Chandler, F.W., Kaplan, W. and Ajello, L. (1980). A Colour Atlas and Textbook of the Histopathoiogy of Mycotic Diseases. (London: Wolfe Medical).Google Scholar
  7. 7.
    Katzenstein, A. A., Sale, S. C. and Greenberger, P. A. (1983). Pathologic findings in allergic aspergillus sinusitis. Am. J. Surg. Pathol., 7, 439–443.PubMedCrossRefGoogle Scholar
  8. 8.
    Khaleque, K. A. (1963). Interesting findings in rhinosporidiosis. Am. J. Med., 35, 566–568.PubMedCrossRefGoogle Scholar
  9. 9.
    McClatchie, S., Warambo, M. W. and Bremner, A. D. (1969). Myospherulosis. A previously unreported disease? Am. J. Clin. Pathol., 51, 699–704.PubMedGoogle Scholar
  10. 10.
    Rosai, J. (1978). The nature of myospherulosis of the upper respiratory tract. Am. J. Clin. Pathol., 69, 475–481.PubMedGoogle Scholar
  11. 11.
    Compagno, J. and Hyams, V. J. (1976). Nasal polyposis with atypical stroma. Arch. Pathol. Lab. Med., 100, 224–226.PubMedGoogle Scholar
  12. 12.
    Graham, J. and Michaels, L. (1978). Cholesterol granuloma of the maxillary antrum. Clin. Otolaryngol., 3, 155–160.PubMedCrossRefGoogle Scholar
  13. 13.
    Carrington, C. B. and Liebow, A. A. (1970). Pulmonary veno-occlusive disease. Hum. Pathol., 1, 322–324.PubMedCrossRefGoogle Scholar
  14. 14.
    Godman, G. C. and Churg, J. (1954). Wegener’s granulomatosis; pathology and review of the literature. Am. Med. Assoc. Arch. Pathol., 58, 533–553.Google Scholar
  15. 15.
    Weiss, M. A. and Crissman, J. D. (1984). Renal biopsy findings in Wegener’s granulomatosis: segmental necrotizing glomerulonephritis with glomerular thrombosis. Hum. Pathol., 15, 942–956Google Scholar
  16. 16.
    van der Woude, F. J., Rasmussen, N., Lobatto, S. et al. (1985). Autoantibodies against neutrophils and monocytes: tool for diagnosis and marker of disease activity in Wegener’s granulomatosis. Lancet, 1, 425–442.PubMedCrossRefGoogle Scholar

Copyright information

© L. Michaels 1990

Authors and Affiliations

  • L. Michaels
    • 1
  1. 1.Department of Histopathology Institute of Laryngology and OtologyUniversity College and Middlesex School of MedicineLondonEngland

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