Abstract
Pubertal maturation can be defined as the reactivation or disinhibition of a suppressed hypothalamic GnRH pulse generator system. Increased amplitude of pulsatile GnRH release and increased stimulation of pituitary gonadotropes, particularly at night, results in gonadal maturation and secretion [1–3].
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References
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© 1990 Kluwer Academic Publishers
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Kaplan, S.L., Stephure, D., Knezvic, J., Grumbach, M.M. (1990). Precocious Puberty: Pathophysiology and Treatment. In: Vickery, B.H., Lunenfeld, B. (eds) GnRH Analogues in Cancer and Human Reproduction. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0725-6_8
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DOI: https://doi.org/10.1007/978-94-009-0725-6_8
Publisher Name: Springer, Dordrecht
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