Advertisement

The Use of GnRH Analogues for Synchronization of Oocyte Donation

  • P. Devroey
  • M. Camus
  • J. De Schacht
  • I. Khan
  • J. Smitz
  • C. Staessen
  • L. Van Waesberghe
  • A. Wisanto
  • A. C. Van Steirteghem

Abstract

Since the first pregnancy and delivery in a patient with absent ovaries [1] more pregnancies have been reported after oocyte donation. Synchrony of the donor’s and recipient’s cycles is mandatory. We here report the synchronization of the donor’s cycle to the recipient’s substituted cycle using a long and short protocol of GnRH analogues in combination with hMG and HCG.

Keywords

Embryo Transfer Ovarian Stimulation GnRH Analogue Oocyte Donation Donation Program 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Lutjen, P, Trounson, A, Leeton, J, Findlay, J, Wood, C and Renou, P (1984). The establishment and maintenance of pregnancies using in vitro fertilization and embryo donation in a patient with primary ovarian failure. Nature, 307, 174PubMedCrossRefGoogle Scholar
  2. 2.
    Devroey, P, Wisanto, A, Smitz, J, Braeckmans, P, Van Waesberghe, L and Van Steirteghem, AC (1987). Ovarian stimulation including in vitro fertilization. Ann Biol Clin, 45, 346Google Scholar
  3. 3.
    Wisanto, A, Braeckmans, P, Camus, M, Devroey, P. Khan, I, Staessen, C, Smitz, 0, Van Waesberghe, L and Van Steirteghem, AC (1987). Perurethral ultrasound guided ovum pick-up. J Vitro Fertil Embryo Transfer, (in press)Google Scholar
  4. 4.
    Devroey, P, Braeckmans, P, Smitz, J, Van Waesberghe, L, Wisanto, A and Van Steirteghem, AC (1986). Pregnancy after translaparoscopic zygote intra-fallopian transfer in a patient with sperm antibodies. Lancet I, 1329.Google Scholar
  5. 5.
    Van Steirteghem, AC, Devroey, P, Heip, J, Liebaers, 1, Liu, Y, Naaktgeboren, N, Olbrechts, H, Temmerman, M and Verhoeven, N (1984). Monitoring of patients in an in vitro fertilization and embryo transfer program. In: Bettocchi, S, Carenza, L, Loverro, G and Sadurny, G (eds.) “Human in Vitro Fertilization and Embryo Transfer and Early Embryo Development”. pl87 (Rome: CIC Edizioni Internationali)Google Scholar
  6. 6.
    Trounson, A and Mohr, L (1984). Human pregnancy following cryopreservation, thawing and transfer of an eight-cell embryo. Nature, 305, 707CrossRefGoogle Scholar
  7. 7.
    Lasalle, B, Testart, J and Renard, JP (1985). Human embryo features that influence the success of cryopreservation with the use of 1, 2 propanediol. Fertil Steril, 44, 645Google Scholar
  8. 8.
    Van Steirteghem, AC, Van den Abbeel, E, Braechmans, P, Camus, M, Khan, I, Smitz, J, Staessen, C, Van Waesberghe, L, Wisanto, A and Devroey, P (1987). Pregnancy with a frozen-thawed embryo in a woman with primary ovarian failure. N Engl J Med, 317, 113PubMedCrossRefGoogle Scholar
  9. 9.
    Van Steirteghem, AC, Van den Abbeel, E, Van Waesberghe, L, Braecknans, P, Khan, I, Nijs, M, Smitz, J, Staessen, C, Wisanto, A, and Devroey, P (1987). Cryopreservation of human embryos obtained after gamete intra-fallopian transfer and/or in vitro fertilization. Human Reprod, 2, 593Google Scholar
  10. 10.
    Navot, D, Laufer, N, Kopolovic, J, Rabinowitz, R, Birkenfeld, A, Lewin, A, Granat, Margalioth, EJ and Schenker, OG (1986). Artificially induced endometrial cycle and establishment of pregnancies in the absence of ovaries. N Engl J Med, 314, 806PubMedCrossRefGoogle Scholar
  11. 11.
    Warnock, M (ed.) (1985). “A Question of Life”. (Oxford: Basil Blackwell Ltd.)Google Scholar
  12. 12.
    Smitz, J, Devroey, P, Braeckmans, P, Camus, M, Khan, I. Staessen, C, Van Waesberghe, L, Wisanto, A and Van Steirteghem, AC.(1987). Management of failed cycles in an IVF (GIFT) program with the combination of a GnRH analogue and hMG. Human Reprod, 2, 309Google Scholar
  13. 13.
    Devroey, P, Smitz, J, Camus, M, Deschacht, J, Van Waesberghe, L, Wisanto, A, Bourgain, CI and Van Steirteghem, AC. La phase luteale apres traitement a la Busereline. Contrac Sexual Fertil (in press)Google Scholar
  14. 14.
    Devroey, P, Braeckmans, P, Camus, M, Khan, I, Smitz, J, Staessen, C, Van den Abbeel, E, Van Waesberghe, L, Wisanto, A and Van Steirteghem, AC (1987). Pregnancies after replacement of fresh and frozen-thawed embryos in a donation program. In: Feichtinger, N and Kemeter, P (eds.) “Future Aspects of Human In Vitro Fertilization” p.133. (Heidelberg: Springer-Verlag)Google Scholar

Copyright information

© Kluwer Academic Publishers 1990

Authors and Affiliations

  • P. Devroey
    • 1
  • M. Camus
    • 1
  • J. De Schacht
    • 1
  • I. Khan
    • 1
  • J. Smitz
    • 1
  • C. Staessen
    • 1
  • L. Van Waesberghe
    • 1
  • A. Wisanto
    • 1
  • A. C. Van Steirteghem
    • 1
  1. 1.Centre for Reproductive MedicineMedical Campus, Vrije Universiteit BrusselBelgiumBrussels

Personalised recommendations