Acute Leukaemias

  • B. Frisch
  • R. Bartl
Part of the Current Histopathology book series (CUHI, volume 15)


Traditionally, the diagnosis of acute leukaemia has been, and still is, based on peripheral blood counts and on routinely stained smears of blood and bone marrow aspirates1 (except in cases of a dry tap). Electron microscopy, cytogenetics, cytochemistry, presence of Auer rods, immunological (monoclonal antibodies) and enzyme markers are required for categorization and phen-otyping2–8. In some cases, especially those with some degree of differentiation, the type of leukaemia may be recognized in sections of the biopsies; for example erythroblastic, megakaryoblastic and monoblastic cell lines9.


Bone Marrow Acute Myeloid Leukaemia Bone Marrow Biopsy Bone Marrow Infiltration Peripheral Blood Count 
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Copyright information

© B. Frisch and R. Bartl 1990

Authors and Affiliations

  • B. Frisch
    • 1
  • R. Bartl
    • 2
  1. 1.Institute of Haematology, Ichilov Hospital and Sackler Faculty of MedicineTel-Aviv UniversityIsrael
  2. 2.Bone Marrow Diagnosis Dept. of Internal Medicine “Innenstadt”University of MunichGermany

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