Metastases in the Bone Marrow

  • B. Frisch
  • R. Bartl
Part of the Current Histopathology book series (CUHI, volume 15)


The introduction of advanced technology for obtaining biopsies under radiological guidance, improvements in biopsy needles, the development of specific monoclonal antibodies and tumour markers, and the progress in histological techniques have led to a widespread upsurge of interest in examination of the bone marrow for detection of metastases1-11. Moreover, evidence has now accumulated that any primary tumour has the ability to spread as soon as it is established and has access to lymphatic or blood vessels. Metastatic potential is also related to the cellular heterogeneity of the primary tumour12.


Breast Cancer Bone Marrow Bone Marrow Biopsy Prussian Blue Skeletal Metastasis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© B. Frisch and R. Bartl 1990

Authors and Affiliations

  • B. Frisch
    • 1
  • R. Bartl
    • 2
  1. 1.Institute of Haematology, Ichilov Hospital and Sackler Faculty of MedicineTel-Aviv UniversityIsrael
  2. 2.Bone Marrow Diagnosis Dept. of Internal Medicine “Innenstadt”University of MunichGermany

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