The pharmacokinetics of azapropazone

  • J. C. McElnay
  • F. S. Walker

Abstract

The subject of pharmacology can conveniently be divided into two subsections, namely pharmacodynamics and pharmacokinetics. While pharmacodynamics deals with the therapeutic effects (both desirable and undesirable), i.e. what the drug does to the organism, pharmacokinetics deals with the kinetics of the processes of absorption, distribution and elimination of the drug, i.e. how the organism treats the drug. A careful study of the pharmacokinetic profile of a drug is desirable since the magnitude of both the desired therapeutic response and toxicity are often closely related to the concentration of the drug at its site(s) of action. This latter concentration can often be correlated with serum concentrations of the drug and it is via careful evaluation of serum drug concentrations, post administration, that the preliminary pharmacokinetic profile of a drug can be established.

Keywords

Human Serum Albumin Synovial Fluid Peak Plasma Concentration Plasma Protein Binding Free Fraction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic Publishers 1989

Authors and Affiliations

  • J. C. McElnay
  • F. S. Walker

There are no affiliations available

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