Abstract
Since numerous detailed accounts of transplantation immunology appear elsewhere in the literature1–3 and the mechanism of allograft destruction is outlined in Chapter 14, this chapter will concentrate only on those pretransplant immunological aspects that are of practical clinical importance before a cardiac transplant is performed. Four topics will be discussed: (1) the necessity for donor-recipient ABO blood group compatibility, (2) the role of human leukocyte antigen (HLA) matching, (3) the lymphocytotoxic crossmatch test and the problem of preformed antibodies, and (4) the effect of pretransplant blood transfusions in recipients of cardiac allografts.
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References
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Toit, E.D.D., Oudshoorn, M., Cooper, D.K.C. (1990). Pretransplant Immunological Considerations. In: Cooper, D.K.C., Novitzky, D. (eds) The Transplantation and Replacement of Thoracic Organs. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0711-9_8
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