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Carbonic Anhydrases: The Mechanistic, Spectroscopic, and Model Studies

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Enzymatic and Model Carboxylation and Reduction Reactions for Carbon Dioxide Utilization

Part of the book series: NATO ASI Series ((ASIC,volume 314))

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Abstract

The Carbonic Anhydrases (CAs) are Zn2+-containing enzymes that occur ubiquitously in Nature. They have been extensively studied with respect to their ability to hydrate CO2 and dehydrate HCO3 −. The first part of the following discussion will focus on the recent studies with the enzyme that have in total, led to the formulation of a detailed mechanism of action, namely, the “zinc hydroxide” mechanism. The second part of the discussion deals with the simpler chemical models that mimic the spectroscopic properties of cobalt CA, and others which mimic the catalytic properties.

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  1. Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada, T6G 2G2

    R. S. Brown

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  1. Department of Chemistry, University of Bari, Bari, Italy

    M. Aresta

  2. Central Research & Development Department, E.I. du Pont de Nemours & Co., Wilmington, Delaware, USA

    J. V. Schloss

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Brown, R.S. (1990). Carbonic Anhydrases: The Mechanistic, Spectroscopic, and Model Studies. In: Aresta, M., Schloss, J.V. (eds) Enzymatic and Model Carboxylation and Reduction Reactions for Carbon Dioxide Utilization. NATO ASI Series, vol 314. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0663-1_9

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