Molecular Chaperones and Chloroplast Biogenesis
It is now two years since it was first proposed that many cellular processes require the mediation of a family of proteins termed molecular chaperones (1). During these two years evidence supporting the concept that molecular chaperones mediate universal cellular functions has grown (2–4). More and more proteins are being identified which carry out chaperone roles in a growing variety of cellular processes. In this article we briefly discuss the concept of molecular chaperones, and speculate on their possible roles in chloroplast biogenesis in the hope of stimulating research in this area. It is particularly appropriate to discuss the chaperone concept at this Congress, since its origin springs from research on the assembly of the photosynthetic enzyme Rubisco carried out at the University of Warwick since 1979 (5).
KeywordsMolecular Chaperone Thylakoid Lumen Coxiella Burnetii mRNA Turnover Chloroplast Biogenesis
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