Cancer in the Esophagus: Principles of Laser Treatment

  • Rene Lambert
Part of the Developments in Gastroenterology book series (DIGA, volume 10)


The 5 year survival rate for esophageal cancer is very low in cancer registries. The crude data (around 3 percent) are not significantly improved when multicentric surveys collect cases either in the surgical, or in the radiation therapy departments, reaching respectively 4 and 6 percent (1, 2). Figures improve when restricted to cases effectively receiving radical treatment. However, the current therapy available in the period 1960–1970 does not significantly alter the natural history of the disease. Radical curative resection of the tumor is the best procedure available, with a 5 year survival rate reaching 20 percent in occidental countries and 50 percent in China or Japan (3, 4, 5). However, curative surgery is only feasible for a small percentage of cases. During the last 10 years, a tendency to improved efficacy of therapy has been observed with a drastic reduction in the post-operative mortality and morbidity, a higher ratio of ‘effectiveness to side effects’ in radiation therapy (linear accelerator, computerized dose assessment…) and now chemotherapy with new agents (of which the main is cisplatin). An increased survival rate at 1 and 2 years is obtained while long term data are not yet available.


Esophageal Cancer Squamous Cell Cancer Bronchial Tree Oesophageal Squamous Cell Carcinoma Esophageal Obstruction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Kluwer Academic Publishers 1990

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  • Rene Lambert

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