Significance of pericardial effusion in acute myocardial infarction

  • Enrique Galve
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 108)


Classically, pericardial effusion during myocardial infarction had been considered rare (1–3). Echocardiography provides an excellent method to establish the prevalence of pericardial effusion (4) in the evolution of myocardial infarction.


Acute Myocardial Infarction Unstable Angina Pericardial Effusion Pericardial Effusion Pericardial Fluid 
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  1. 1.
    Parkinson J, Bedford E. Cardiac infarction and coronary thrombosis. Lancet 1928; 1:4–11.CrossRefGoogle Scholar
  2. 2.
    Master AM, Jaffe HL. Coronary artery thrombosis with pericardial effusion. JAMA 1935; 104:1212–1214.Google Scholar
  3. 3.
    Wolff L. Diagnostic implications of pericardial, pleural and pulmonary involvement in cardiovascular disease. N Engl J Med 1951; 244:965–970.PubMedCrossRefGoogle Scholar
  4. 4.
    Feigenbaum H. Echocardiographic diagnosis of pericardial effusion. Am J Cardiol 1970; 26:475–479.PubMedCrossRefGoogle Scholar
  5. 5.
    Gibson AT, Segal MB. A study of the composition of pericardial fluid, with special reference to the probable mechanism of fluid formation. J Physiol (Lond) 1978; 277:367–377.Google Scholar
  6. 6.
    Thadani U, Chopra MP, Aber CP, Portal RW. Pericarditis after acute myocardial infarction. Br Med J 1971; 2: 135–137.PubMedCrossRefGoogle Scholar
  7. 7.
    Toole JC, Silverman ME. Pericarditis of acute myocardial infarction. Chest 1975; 67:647–653.PubMedCrossRefGoogle Scholar
  8. 8.
    Lichstein E, Liu HM, Gupta P. Pericarditis complicating acute myocardial infarction. Incidence and complications and significance of electrocardiogram on admission. Am Heart J 1974; 87:242–252.CrossRefGoogle Scholar
  9. 9.
    Dressler W. The post—myocardial infarction syndrome. A report of forty four cases. Arch Int Med 1959; 103:28–42.Google Scholar
  10. 10.
    Goldberg RJ, Gore JM, Dalen JE. The role of anticoagulant therapy in acute myocardial infarction. Am Heart J 1984; 108:387–393.Google Scholar
  11. 11.
    Chesebro JH, Fuster V. Antithrombotic therapy for acute myocardial infarction: mechanisms and prevention of deep venous, left ventricular, and coronary artery thromboembolism. Circulation 1986; 74 (suppl III): 1–10.Google Scholar
  12. 12.
    Bates RJ, Beutler S, Resnekov L, Anagnostooulos CE. Cardiac rupture–challenge in diagnosis and management. Am J Cardiol 1977: 40:429–437.PubMedCrossRefGoogle Scholar
  13. 13.
    Norris RM, Sammel NL. Predictors of late hospital death in acute myocardial infarction. Prog Cardiovasc Dis 1980; 23:129–140.PubMedCrossRefGoogle Scholar
  14. 14.
    Galve E, Garcia-del-Castillo H, Evangelista A, Batlle J, Permanyer-Miralda G, Soler-Soler J. Pericardial effusion in the course of acute myocardial infarction: incidence, natural history, and clinical relevance. Circulation 1986; 73:294–299.PubMedCrossRefGoogle Scholar
  15. 15.
    Horowitz MS, Schultz CS, Stinson EB, Harrison DC, Popp PL. Sensitivity and specificity of echocardiographic diagnosis of pericardial effusion. Circulation 1974; 50:239–247.PubMedGoogle Scholar
  16. 16.
    Weitzman LB, Tinker WP, Kronzon I, Cohen ML, Glassman E, Spencer FC. The incidence and natural history of pericardial effusion after cardiac surgery. An echocardiographic study. Circulation 1984; 69:506–511.PubMedCrossRefGoogle Scholar
  17. 17.
    Kaplan K, Davidson R, Parker M, Przybylek J, Light A, Bresnahan D, Ribner H, Talano JV. Frequency of pericardial effusion as determined by M mode echocardiography in acute myocardial infarction. Am J Cardiol 1985; 55:335–337.PubMedCrossRefGoogle Scholar
  18. 18.
    Somolinos M, Violán S, Sanz R, Marrero P. Early pericarditis after acute myocardial infarction: A clinical echocardiographic study. Crit Care Med 1987; 15:648–651.PubMedCrossRefGoogle Scholar
  19. 19.
    Pierard LA, Albert A, Henrard L, Lempereur P, Sprynger M, Carlier J, Kulbertus HE. Incidence and significance of pericardial effusion in acute myocardial infarction as determined by two—dimensional echocardiography. J Am Coll Cardiol 1986; 8:517–520.PubMedCrossRefGoogle Scholar
  20. 20.
    Wunderink RG. Incidence of pericardial effusions in acute myocardial infarctions. Chest 1984; 85:494–496.PubMedCrossRefGoogle Scholar
  21. 21.
    Savage DD, Garrison RJ, Brand F, Anderson SJ, Castelli WP, Kannel WB, Feinleib M. Pre—valance and correlates of posterior extra echocardiographic spaces in a free—living population based sample (The Framingham Study). Am J Cardiol 1983; 51:1207–1212.PubMedCrossRefGoogle Scholar
  22. 22.
    Rhode EA. Physiology of the normal pericardium in pericardial disease. In: Reddy PS, Leon DF, Shaver JA. eds. New York: Raven Press, 1982:33.Google Scholar
  23. 23.
    Rifkin RD, Isner JM, Carter BL, Bankoff MS. Combined posteroanterior subepicardial fat simulating the echocardiographic diagnosis of pericardial effusion. J Am Coll Cardiol 1984; 3:1333–1339.PubMedCrossRefGoogle Scholar
  24. 24.
    Berger M, Bobak L, Jelveh M, Goldberg E. Pericardial effusion diagnosed by echocardiography. Clinical and electrocardiographic findings in 171 patients. Chest 1978; 74:724–729.CrossRefGoogle Scholar
  25. 25.
    Phibbs B. “Transmural” versus “subendocardial” myocardial infarction: an electrocardiographic myth J Am Coll Cardiol 1983; 1:561–564.PubMedCrossRefGoogle Scholar
  26. 26.
    Spodick DH Q-wave infarction versus ST infarction. Nonspecificity of electrocardiographic criteria for differentiating transmural and non-transmural lesions. Am J Cardiol 1983; 51:913–915.PubMedCrossRefGoogle Scholar
  27. 27.
    . Editorial Pericardial effusion after acute myocardial infarction. Lancet 1986; 1:1015–1016.Google Scholar
  28. 28.
    Rosenbaum FF, Levine SA. Prognostic value of various clinical and electrocardiographic features of acute myocardial infarction. Arch Int Med 1941; 68:913–917.Google Scholar
  29. 29.
    Mintz SS, Katz LN. Recent myocardial infarction. An analysis of five hundred and seventy-two cases. Arch Int Med 1947; 80:205–236.Google Scholar
  30. 30.
    Niarchos AP, McKendrick CS. Prognosis of pericarditis after acute myocardial infarction. Br Heart J 1973; 35:49–54.PubMedCrossRefGoogle Scholar
  31. 31.
    Liem KL, Durrer D, Lie KI, Wellens HJJ. Pericarditis of acute myocardial infarction. Lancet 1975; 2:1004–1006.PubMedCrossRefGoogle Scholar
  32. 32.
    Guillevin L, Valere PE. Pericarditis in acute myocardial infarction. Lancet 1976; 1:429.PubMedCrossRefGoogle Scholar
  33. 33.
    Sawaya JI, Mujais SK, Armenian HK. Early diagnosis of pericarditis in acute myocardial infarction. Am Heart J 1980; 100:144–151.PubMedCrossRefGoogle Scholar
  34. 34.
    Krainin FM, Flessas AP, Spodick DH. Infarction associated pericarditis. Rarity of diagnostic electrocardiogram. N Engl J Med 1984; 311:1211–1214.PubMedCrossRefGoogle Scholar
  35. 35.
    Tofler GH, Muller JE, Stone PH, Willich SN, Davis VG, Poole K, Robertson T, Braunwald E, MILIS study group. Pericarditis in acute myocardial infarction: Characterization and clinical significance. Am Heart J 1989; 117:86–92.PubMedCrossRefGoogle Scholar
  36. 36.
    Aarseth S, Lange HF. The influence of anticoagulant therapy on the occurrence of cardiac rupture and hemopericardium following heart infarction. I. A study of 89 cases of hemopericardium (81 of them cardiac ruptures). Am Heart J 1958; 56: 250 – 256.PubMedCrossRefGoogle Scholar
  37. 37.
    Waldrom BR, Fennell RH Jr, Castleman B, Bland EF. Myocardial rupture and hemopericardium associated with anticoagulant therapy; a post—mortem study. N Engl J Med 1954; 251:892–894.CrossRefGoogle Scholar
  38. 38.
    Goldstein R, Wolff L. Haemorrhagic pericarditis in acute myocardial infarction treated with bis hydroxicumarin. JAMA 1951; 146:616–621.Google Scholar
  39. 39.
    . Rose OA, Ott RH Jr, Maier HC. Hemopericardium with tamponade during anticoagulant therapy of myocardial infarction: report of case with recovery following pericardiotomy. JAMA 1953; 152:1221–1223.Google Scholar
  40. 40.
    Khanderia BK, Shub C, Nishimura RA, Miller FA Jr., Seward JB, Tajik AJ. To anticoagulate or not: implications for the management of patients with acute myocardial infarction complicated by both left ventricular thrombus and pericardial effusion. Can J Cardiol 1987; 3:173–176.Google Scholar
  41. 41.
    López-Sendón J, González A, Sotillo J. Diagnostic approach to subacute ventricular rupture following acute myocardial infarction. X World Congress of Cardiology, Washington (Abstract Book) 1986;100.Google Scholar
  42. 42.
    Lichstein E, Arsura E, Hollander G, Greengart A, Sanders M. Current incidence of postmyocardial infarction (Dressler’s) syndrome. Am J Cardiol 1982; 50:1269–1271.PubMedCrossRefGoogle Scholar

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© Kluwer Academic Publishers 1990

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  • Enrique Galve

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