Effects of abrupt coronary occlusion on Doppler ejection dynamics in man
In experimental animals, brief periods of acute coronary artery occlusion can result in a marked impairment of regional left ventricular wall function [1–3]. The magnitude of global impairment of left ventricular function that accompanies regional wall motion abnormalities is dependent upon the extent of left ventricular ischemic mass . Recently, with the advent of percutaneous transluminal coronary angioplasty (PTCA), transient occlusion of a coronary artery with the angioplasty balloon provided a model through which regional and global left ventricular function can be assessed in patients during brief periods of myocardial ischemia.
KeywordsCoronary Occlusion Collateral Vessel Peak Acceleration Balloon Inflation Regional Wall Motion Abnormality
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- 1.Theroux, P, Franklin D, Ross J, Jr, Kemper WS. Regional myocardial function during coronary artery occlusion and its modification by pharmacologic agents in the dog. Circ Res 1974; 35:396–908.Google Scholar
- 7.Serruys PW, Wijns W, van den Brand M, Slager C, Schuurbiers JCH, Hugenholtz PG, Brower RW. Left ventricular function during transluminal angioplasty: a hemodynamic and angiographic study. Acta Med Scand 1984; 694:197–206.Google Scholar
- 11.Hauser AM, Gangadharan V, Ramos RG, Gordon S, Timmins GC, Dudlets P. Sequence of mechanical, electrocardiographic and clinical effects of repeated coronary artery occlusion in human beings: Echocardiographic observations during coronary angioplasty. J Am Coll Cardiol 1985; 5:193–197.PubMedCrossRefGoogle Scholar
- 14.Voyles WF, Anderson JL, Teague SM, Prasad R, Olson E, Schechter E, Thadani U. Abrupt coronary occlusion and left ventricular ejection during coronary angioplasty. Am J Noninvas Cardiol 1989; 3:125–130.Google Scholar