How to critically appraise a clinical trial
The prescription of medications is a daily activity for most physicians. The act of prescribing incorporates a number of factors including issues related to effectiveness, appropriate use, comparability with other medications, adverse events and cost. The answers to most of these issues can be found within the body of the available medical literature. But therein lies a dilemma. Clinicians wish to base their therapeutic decisions on scientific data but are often overwhelmed by the number of case reports, open series and other therapeutic trials that are published each year.
KeywordsInflammatory Bowel Disease Ulcerative Colitis Active Medication Pill Count Open Series
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- 1.Department of Clinical Epidemiology and Biostatistics, McMaster University Health Sciences Centre. How to read medical journals: V. To distinguish useful from useless or even harmful therapy. CMAJ. 1981; 124: 1156–62.Google Scholar
- 2.Meinert CL. Clinical trials design conduct, and analysis. Oxford: Oxford University Press; 1986.Google Scholar