The Expression of HLA-DR, IL-2R, ICAM-1 and TNF Alpha Molecules as Possible Prognostic Elements of Hypertrophic Scarring in Burns
Patients suffering from hypertrophic scarring secondary to extensive burns have to expect modifications in their social and working life, together with lengthy physiotherapeutic and surgical procedures, in a background of uncertainty as regards the long-term evolution of the scars and the quality of the final result. It is thus important to study the little known aetiopathogenic factors involved, in order to propose new therapeutic approaches in burn scars.
KeywordsMajor Histocompatibility Complex Class Lichen Planus Hypertrophic Scar Mycosis Fungoides Bullous Pemphigoid
Unable to display preview. Download preview PDF.
- Castagnoli, C, Stella, M., Peruccio, D., Richiardi, P. and Magliacani, G. (1990). HLA susceptibility factors in hypertrophic scarring. Proceedings of the 8th International Congress on Burn Injuries, New Delhi, India.Google Scholar
- Jacob, C. O., Fronek, Z., Lewis, G. D., Koo, M., Hansen, J. A. and McDevitt, H. O. (1990). Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: relevance to genetic predisposition to systemic lupus erythematosus. Proc. Natl Acad. Sci. USA, 87, 1233.PubMedCrossRefGoogle Scholar
- Stella, M., Castagnoli, C, Magliacani, G. and Richiardi P. (1989). Fisiopatologia della cicatrice ipertrofica (revisione bibliografica). Riv. Ital. Chir. Plast., 21, 199.Google Scholar