Efficacy of Haptoglobin in Haemolysis and Prevention of Acute Renal Disorders Following Severe Burn Injury

  • Muneo Ohta
  • Hiroaki Terada


In Japan recent interest in burn injury has focused on the survival rate, and the pathophysiology of severely burned patients. The main causes of death in severely burned patients are sepsis and acute organ failure, while acute renal failure secondary to haemoglobinuria also occurs as a cause of death in early stages.


Acute Renal Failure Blood Urea Nitrogen Free Haemoglobin Burned Patient Free Water Clearance 
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  1. Aikawa, N., Ishibiki, K., Okusawa, S et al (1984). Use of haptoglobin to prevent renal damage due to hemolysis in extensive third-degree burns. J. Burn Care Rehab., 5, 20–4.CrossRefGoogle Scholar
  2. Funakoshi, S., Oomura, T., Oshiro, T. and Hong SD. (1976). Haptoglobin: its isolation and clinical significance. In Trace components of plasma: Isolation and clinical significance New York: Alan R. Liss, 397–410.Google Scholar
  3. Yoshioka, T., Sugimoto, T., Ukai, T. and Oshiro, T. 1985. Haptoglobin therapy for possible prevention of renal failure following thermal injury: A clinical study. J. Trauma, 25, 281–7.PubMedCrossRefGoogle Scholar

Copyright information

© Kluwer Academic Publishers 1995

Authors and Affiliations

  • Muneo Ohta
  • Hiroaki Terada
    • 1
  1. 1.Osaka Prefectural Senri Critical Care Medical CenterOsakaJapan

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