Myocardial perfusion imaging by SPECT
Over the last decade, substantial advancements in the field of myocardial perfusion scintigraphy have markedly improved the diagnosis and subsequent evaluation of patients with coronary artery disease (CAD). These improvements have mainly originated from the transition of planar imaging to single-photon emission computed tomography (SPECT). In addition, several new technetium 99m (99mTc) based radiopharmaceuticals have entered the clinical arena which are very suitable for SPECT imaging. Lastly, new pharmacological stress agents have been developed. In this era of continuing cost containment, myocardial perfusion scintigraphy using SPECT imaging has emerged as a highly cost-effective noninvasive modality for guiding patient management.
This chapter will concentrate on the merits of SPECT imaging, the use of the appropriate SPECT imaging protocols both for thallium-201 (201Tl) and 99mTc-labeled agents, and the application of pharmacologic stress in myocardial perfusion SPECT imaging.
KeywordsMyocardial Perfusion Myocardial Perfusion Imaging Perfusion Defect SPECT Imaging Myocardial Perfusion Scintigraphy
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