Blood flow measurements using 3D distance-concentration functions derived from digital x-ray angiograms

  • Alexander M. Seifalian
  • David J. Hawkes
  • Christopher Bladin
  • Alan C. Colchester
  • Kenneth E. Hobbs
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 186)


We describe a method for measurement of velocity flow, absolute cross-sectional area and path length of identified arteries for high frame rate biplane x-ray angiograms. The system has been extensively validated with phantoms for vessel calibres from 3 to 6 mm and flow rates encompassing those expected “in-vivo”. Mean volume flow agreed with electromagnetic flow meter readings to within 9% and peak flow agreed to within 10% for velocity flow below 1 m/sec when measuring a 150 mm length of artery at a framing rate of 25 frames per sec. Path lengths of bent wire were measured with an error of less than 2%. We present initial results using these measures to study the haemodynamics of the circulation from the arch of the aorta to the circle of Willis.


Digital Subtraction Angiography Vessel Segment Blood Flow Measurement Flow Waveform Epipolar Line 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Kluwer Academic Publishers 1996

Authors and Affiliations

  • Alexander M. Seifalian
  • David J. Hawkes
  • Christopher Bladin
  • Alan C. Colchester
  • Kenneth E. Hobbs

There are no affiliations available

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