Principles of Antibody Catalysis

  • Donald Hilvert
Part of the NATO ASI Series book series (NSSE, volume 320)


A wide range of chemical transformations can be catalyzed by antibody molecules elicited with rationally designed transition state analogs. The development of catalytic antibodies consequently represents one of the most versatile and general strategies for creating new enzymes to emerge in the last several years. Recent advances in the production and characterization of these agents are reviewed.


Antibody Molecule Catalytic Antibody Claisen Rearrangement Chorismate Mutase Transition State Analog 
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Copyright information

© Kluwer Academic Publishers 1996

Authors and Affiliations

  • Donald Hilvert
    • 1
  1. 1.Departments of Chemistry and Molecular BiologyThe Scripps Research InstituteLa JollaUSA

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