Multivariable Control of a Continuous Culture
Multivariable control of both pH and ammonium levels in an aerobic continuous yeast culture was demonstrated. A buffered glucose feed was used for pH control. This control loop was coupled with ammonium control using an on-line ammonia electrode suspended above a pH-adjusted sample stream from the fermentor. The dilution rate of the culture was the sum of the two individual feed rates. The advantages and implications of multivariable feedback control in continuous fermentation are discussed.
KeywordsFeed Rate Dilution Rate Continuous Culture Caustic Solution Closed Loop Response
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