Strategies for Bioreactor Scale-Up

  • F. Mavituna
Part of the NATO ASI Series book series (NSSE, volume 305)


Scale-up has been one of the major problems in bioprocess technology. Earlier methods of trial-and-error have now been replaced by those which involve the understanding of the fundamental phenomena, at least for the simpler cases. For more complicated heterogeneous systems the employment of various rules of thumb is still widely practised. A summary of various strategies for bioreactor scale-up is given below.


Heat Transfer Coefficient Dimensional Analysis Dimensionless Group Bioprocess Technology Regime Analysis 
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Copyright information

© Kluwer Academic Publishers 1996

Authors and Affiliations

  • F. Mavituna
    • 1
  1. 1.Department of Chemical EngineeringUniversity of Manchester Institute of Science and Technology’ManchesterUK

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