• Scott L. Dax


Anti-infective chemotherapy is the science of administering chemical agents to treat infectious diseases. This practice has proven to be one of the most successful of all pharmaceutical studies. Historically, the use of anti-infective agents can be credited with saving more human lives than any other area of medicinal therapy discovered to date. Humanity has enjoyed a tremendous increase in life expectancy in the past century; a significant portion of this can be attributed to the control and eradication of infectious pathogens. A better understanding of infectious disease pathogenesis and the importance of sanitation are contributing factors. Regardless, most individuals will become infected with a microbial pathogen many times throughout their lives and in developed countries, anti-infective chemotherapy will be periodically administered. Antibacterials account for the majority of anti-infective agents in comparison to antifungals, antivirals and antiparasitic agents.


Antibacterial Agent Typhoid Fever Rheumatic Fever Antibacterial Drug Toxic Shock Syndrome 
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Further reading

  1. R.E. McGrew and M.P. McGrew (1985)Encyclopedia of Medical History, McGraw-Hill, USA.Google Scholar
  2. G.L. Mandell, R.G. Douglas, Jr. and J.E. Bennett (Eds) (1990)Principles and Practice of Infectious Diseases, 3rd edn, Churchill Livingstone, New York.Google Scholar
  3. J.C. Sherris (Ed.) (1990)Medical Microbiology: An Introduction to Infectious Diseases, 2nd edn, Appleton & Lange, Norwalk, CT.Google Scholar
  4. P.D. Hoeprich (Ed.) (1983)Infectious Diseases, 3rd edn, Harper & Row, Philadelphia, PA.Google Scholar
  5. G.A. Jacoby and G.L. Archer (1991) in ‘New mechanisms of bacterial resistance to antimicrobial agents’, F.H. Epstein (Ed.)New England J. Med., 324, 601.Google Scholar
  6. A.S. Evans and P.S. Brachman (Eds) (1991)Bacterial Infections of Humans: Epidemiology and Control, 2nd edn, Plenum Medical, New York.Google Scholar

Copyright information

© Chapman & Hall 1997

Authors and Affiliations

  • Scott L. Dax
    • 1
  1. 1.Research InstituteThe R.W Johnson PharmaceuticalSpring HouseUSA

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