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Effect of Mg Therapy on the Outcome of Pregnancy in Certain Obstetric Diseases

  • L. Lukacsi
  • A. Sebestyen
  • F. Banhidy
  • A. Laszlo
  • F. Paulin
Chapter

Abstract

Preeclampsia (PE) and intrauterine retardation (IUGR) are known to significantly alter perinatal morbidity, mortality and the outcome of pregnancy. The smooth muscle- relaxant effect of the intravenously applied MgS04 was first described in 1905 [1]. Rissman was the first to use Mg in order to prevent eclampsia in 1916 [2]. The method came into general use first of all in the USA [3,4], followed by the wide-spread use of it both in the prevention and treatment of eclampsia in Europe, too [5,6]. The chemical and biochemical basis of the therapeutic effect was summarized by Gunther et al. [7]. In our study the effect of Mg infusion treatment on pregnancy outcome in patients with PE, IUGR, imminent abortion and imminent premature labor was examined.

Keywords

Magnesium Sulfate Maternal Serum Biochemical Basis Infusion Treatment Premature Labor 
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References

  1. 1.
    Meitzer, S.I., Auer, J. (1905), Physiological and pharmacological studies of magnesium salts. I. General anestesia by subcuteneous injection. Am. J. Physiol. 14, 366.Google Scholar
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  3. Lazard, E.M. (1925) A preliminary report on the intravenous use of magnesium sulfate in puerpal eclampsia. Am. J. Obstet. Gynecol. 9, 178.Google Scholar
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  6. Conradt, A., Weidinger, H., Algayer, H. (1984), reduzierte Frequenz von Gestosen bei betamimetika behandelten Riskoschwangerschaften mit Magnesium-usatztherapie.Geburtsh. U. Frauenheilk, 44, 118.CrossRefGoogle Scholar
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Copyright information

© Kluwer Academic Publishers 1997

Authors and Affiliations

  • L. Lukacsi
    • 1
  • A. Sebestyen
    • 1
  • F. Banhidy
    • 1
  • A. Laszlo
    • 1
  • F. Paulin
    • 1
  1. 1.2nd Department of Ob/GynSemmelweis University of MedicineBudapestHungary

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