Up to now, reports about HIV/AIDS related myelopathy remain rare in China. McArthur collected 186 cases of HIV/AIDS complicated by brain and peripheral nerve lesions in the year of 1987 . Only 13 cases had HIV/AIDS related myelopathy, accounting for 7 %. Levy et al.  reported the occurrence of HIV/AIDS related myelopathy is 2–22 % based on literature analysis. In another group of 150 patients with AIDS, 42 had HIV/AIDS related myelopathy, in which 24 % with spinal degeneration, 38 % with viral infection, 5 % with toxoplasmosis, 2 % with myelitis and the other 31 % with no pathological diagnosis . Surprisingly, myelopathy is commonly found by autopsy. Peter and his fellow researchers  found 50 % of the total 178 patients with AIDS have myelopathy, with 29 % spinal degeneration, 5 % HIV myelitis, 8 % viral infection, 7 % other infections and 2 % lymphoma. Budka  retrospectively reviewed autopsies of 475 death cases from AIDS in 1997 and found that 22.5 % had spinal degeneration, 6 % myelitis, 58 % viral infection and 4.1 % fungal, bacterial and protozoal infections as well as 2.3 % lymphoma. Since the year of 1997, knowledge about the clinical treatment for HIV/AIDS complicated by myelopathy has been greatly improved.
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in to check access.
Anneken K, Fischera M, Evers S, et al. Recurrent vacuolar myelopathy in HIV infection. J Infect. 2006;52(6):e181–3.PubMedCrossRefGoogle Scholar
Bredesen DE, Levy RM, Rosenblum ML. The neurology of human immunodeficiency virus infection. Q J Med. 1988;68(25):665–77.PubMedGoogle Scholar
Budka H. Neuropathology of myelitis, myelopathy, and spinal infections in AIDS. Neuroimaging Clin N Am. 1997;7(3):639–50.PubMedGoogle Scholar
Claeke TR, Barrow G, Glibert DT, et al. A possible case of spinal tuberculosis in a HIV-positive male. West Indian Med J. 2010;59(4):453–4.Google Scholar
England JD, Gronseth GS, Franklin G, et al. Practice parameter: the evaluation of distal symmetric polyneuropathy: the role of laboratory and genetic testing (an evidence-based review): report of the American Academy of Neurology, the American Association of Neuromuscular and Electrodiagnostic Medicine, and the American Academy of Physical Medicine and Rehabilitation. PM&R. 2009;1:5–13.CrossRefGoogle Scholar
Fuller GN. Cytomegalovirus and the peripheral nervous system in AIDS. J Acquir Immune Defic Syndr. 1992;5(Suppl):33–6.Google Scholar
Husstedt IW, Evers S, Reichelt D, et al. Screening for HIV-associated distal-symmetric polyneuropathy in CDC-classification stages 1, 2 and 3. Acta Neurol Scand. 2000;101:183–7.PubMedCrossRefGoogle Scholar
Levy RM, Bredesen DE, Rosenblum ML. Neurological manifestations of the acquired immunodeficiency syndrome(AIDS):experience at UCSF and review of the literature. J Neurosurg. 1985;62(4):475–95.PubMedCrossRefGoogle Scholar
Marra CM, Boutin P, Collier AC. Screening for distal sensory peripheral neuropathy in HIV-infected persons in research and clinical settings. Neurology. 1998;51:1678–81.PubMedCrossRefGoogle Scholar
Maschke M, Kastrup O, Esser S. Incidence and prevalence of neurological disorders associated with HIV since the introduction of highly active antiretroviral therapy (HAART). J Neurol Neurosurg Psychiatry. 2000;69:376–80.PubMedCrossRefGoogle Scholar
McArthur JCN, Hoover DR, Bacellar H, Miller EN, et al. Dementia in AIDS patients : incidence and risk factors. Multicenter AIDS Cohort Study. Neurology. 1993;43(11):2245–52.PubMedCrossRefGoogle Scholar
Molina-Olier O, Tunon-Pitalua M, Alcala-Cerra G, et al. Spinal cord compression due to intraspinal gumma in one patient. Clinical case. Acta Ortop Mex. 2012;26(3):197–201.PubMedGoogle Scholar
Nakamura M, Fujishima S, Hori S, et al. An adult case of cervico-mediastinal tuberculous lymphadenitis. Nihon Kokyuki Gakkai Zasshi. 2000;38(3):223–8.PubMedGoogle Scholar
Peter SA, Brignol YF, Razavi MH, et al. Diffuse hyperpigmentation associated with acquired immunodeficiency syndrome. J Natl Med Assoc. 1992;84(11):977–9.PubMedGoogle Scholar
Petito CK, Navia BA, Cho ES, et al. Vacuolar myelopathy pathologically resembling subacute combined degeneration in patients with the acquired immunodeficiency syndrome. N Engl J Med. 1985;312(14):874–9.PubMedCrossRefGoogle Scholar
Wulff EA, Wang AK, Simpson DM. HIV-associated peripheral neuropathy epidemiology. Pathophysiology and treatment. Drugs. 2000;59(6):1251–60.PubMedCrossRefGoogle Scholar