Fluid–Structure Interaction Modeling of Patient-Specific Cerebral Aneurysms
We provide an overview of the special techniques developed earlier by the Team for Advanced Flow Simulation and Modeling (T★AFSM) for fluid–structure interaction (FSI) modeling of patient-specific cerebral aneurysms. The core FSI techniques are the Deforming-Spatial-Domain/Stabilized Space–Time formulation and the stabilized space–time FSI technique. The special techniques include techniques for calculating an estimated zero-pressure arterial geometry, a special mapping technique for specifying the velocity profile at an inflow boundary with non-circular shape, techniques for using variable arterial wall thickness, mesh generation techniques for building layers of refined fluid mechanics mesh near the arterial walls, a recipe for pre-FSI computations that improve the convergence of the FSI computations, techniques for calculation of the wall shear stress and oscillatory shear index, and arterial-surface extraction and boundary condition techniques. We show, with results from earlier computations, how these techniques work. We also describe the arterial FSI techniques developed and implemented recently by the T★AFSM and present a sample from a wide set of patient-specific cerebral-aneurysm models we computed recently.
KeywordsWall Shear Stress Oscillatory Shear Index Nonlinear Iteration Arterial Geometry Medium Mesh
This work was supported in part by a seed grant from the Gulf Coast Center for Computational Cancer Research funded by John & Ann Doerr Fund for Computational Biomedicine. It was also supported in part by the Rice Computational Research Cluster funded by NSF Grant CNS-0821727. The 3DRA research at the Memorial Hermann Hospital University of Texas Medical School at Houston was supported by generous a funding from the Weatherhead Foundation. We thank Dr. Ryo Torii (University College London) for the inflow velocity data used in the computations and the arterial geometry used in Sect. 6.1.
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