The Verification of a Newly Discovered Hepatitis B Virus Subtype Based on Sequence Analysis
Hepatitis B virus (HBV) infection is one of the most serious global problems to human health. It has great importance to study HBV through the analysis of its phylogenetic tree. There has been previously reported that researchers had found a new HBV subtype in Xishuangbanna, Yunnan, China, named HBV/B6. In this paper, we propose a series of sequence analysis methods on a new data set that contains the reported one. During the analysis, several kinds of bioinformatics software are involved. The experimental results prove the existence of the newly found subtype HBV/B6 of Xishuangbanna in the reported literature. Moverover, the C gene of the newly found subtype contains a reorganization structure of HBV/B and HBV/C, which provides a positive reference for HBV derivation exploration. The conclusion represents certain significance on phylogenetic studies of hepatitis B virus.
KeywordsHepatitis B virus Subtype The X/PreC gene
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