Anti-Diabetes Components in Leaves of Yacon

Conference paper
Part of the Lecture Notes in Electrical Engineering book series (LNEE, volume 269)


The inhibitory effect of four new compounds (smallanthaditerpenic acids A–D) previously isolated from leaves of Smallanthus sonchifolius (yacon) on α-glucosidase were examined and their IC50 were determined to be 0.48, 0.59, 1.00, and 1.17 mg/mL respectively. In addition, a rapid, reliable HPLC method for the analysis of smallanthaditerpenic acids A and C in yacon leaves was established, and the variation in their contents in leaves from plants cultivated in different places and collected at different times of the year were compared. The established analytical method for determining smallanthaditerpenic acids A and C presented good results and could be used as a method for the quality control of S. sonchifolius leaves.


Smallanthus sonchifolius Smallanthaditerpenic acid Diabetes HPLC 


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Copyright information

© Springer Science+Business Media Dordrecht 2014

Authors and Affiliations

  • Zheng Xiang
    • 1
    • 2
  • Chen-Feng Ji
    • 1
    • 2
  • De-Qiang Dou
    • 1
    • 2
    • 3
  • Kuo Gai
    • 3
  1. 1.Engineering Research Center of Natural Anticancer DrugsMinistry of Education, Harbin University of CommerceHarbinChina
  2. 2.Center of Research on Life Science and Environmental ScienceHarbin University of CommerceHarbinChina
  3. 3.College of PharmacyLiaoning University of Traditional Chinese MedicineDalianChina

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