Impact of Scan Duration on PET/CT Maximum Standardized Uptake Value Measurement

Conference paper
Part of the Lecture Notes in Electrical Engineering book series (LNEE, volume 269)

Abstract

Although readily available and convenient to use on PET/CT, SUV measurements are influenced by biologic and technologic factors like injected activity and scan duration. The aim of this study was to investigate the effect of varying scan duration on SUV using standard clinical activities of 18F-FDG. Patient PET/CT images were acquired in list-mode for 6 min in forty 18F-FDG oncology patients with known tumor. For each patient, data were sorted into 10 images of different durations (from 10 s to 6 min). SUVmax were measured for the lesions in the images. Tumor SUVmax were statistically analyzed taking the low-noise 6 min SUVmax as standard. For each of the nine scan duration from 10 s to 5 min, the normalized SUVmax were 1.080 ± 0.1611, 1.041 ± 0.1043, 1.005 ± 0.0732, 1.004 ± 0.0696, 1.005 ± 0.0456, 0.995 ± 0.0452, 0.996 ± 0.0299, 1.001 ± 0.0233, and 1.0002 ± 0.0144, respectively. One-sample t test revealed that the SUVmax biases for scan durations greater than 40 s were not statistically significant. It was concluded that scan duration as short as 40 s could be applied without compromising the quality of SUVmax measure.

Keywords

PET/CT Standardized uptake value Maximum standardized uptake value Quantification Scan duration 

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Copyright information

© Springer Science+Business Media Dordrecht 2014

Authors and Affiliations

  1. 1.Department of Nuclear Medicine, West China HospitalSichuan UniversitySichuangChina

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