Abstract
Wide presence of fasciculation potentials is an important indicator for supporting diagnosis of amyotrophic lateral sclerosis (ALS). This study describes the use of surface electromyography (EMG) techniques for examination of fasciculation potentials in ALS patients. Multi-channel surface electrode arrays were used for fasciculation potential recording, while template matching techniques were used to discriminate whether the recorded fasciculation potentials were from the same or different motor unit origins. The results were assessed using independent processing of selected channels of electrode array surface EMG signals.
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References
Subcommittee on Motor Neuron Diseases of World Federation of Neurology Research Group on Neuromuscular Diseases, El Escorial “Clinical Limits of ALS” Workshop Contributors. El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. J Neurol Sci 1994 124:96–107
Brooks BR, Miller RG, Swash M et al (2000) World Federation of Neurology Group on Motor Neuron Diseases: El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 1:293–299
Nandedkar SD, Barkhaus PE, Sanders DB et al (2000) Some observations on fibrillations and positive sharp waves. Muscle Nerve 23:888–894
de Carvalho M, Dengler R, Eisen A, England JD, Kaji R, Kimura K et al (2008) Electrodiagnostic criteria for diagnosis of ALS. Clin Neurophysiol 119:497–503
Benatar M, Tandan R (2011) The Awaji criteria for the diagnosis of amyotrophic lateral sclerosis: have we put the cart before the horse? Muscle Nerve 43:461–463
Howard RS, Murray NM (1992) Surface EMG in the recording of fasciculations. Muscle Nerve 15:1240–1245
Blok JH, van Dijk P, Dros G, Zwarts MJ, Stegeman DF (2002) A high-density multichannel surface electromyography system for the characterization of single motor units. Rev Sci Instr 73:1887–1897
Lapatki BG, van Dijk JP, Jonas IE, Zwarts MJ, Stegeman DF (2004) A thin, flexible multielectrode grid for high-density surface EMG. J Appl Physiol 96:327–336
Pozzo M, Bottin A, Ferrabone R, Merletti R (2004) Sixty-four channel wearable acquisition system for long-term surface electromyogram recording with electrode arrays. Med Biol Eng Comput 42:455–466
Merletti R, Botter A, Troiano A, Merlo E, Minetto MA (2009) Technology and instrumentation for detection and conditioning of the surface electromyographic signal: State of the art. Clin Biomech (Bristol, Avon) 24(2):122–134
Zhou P (2012) Duration of observation required in detecting fasciculation potentials in amyotrophic lateral sclerosis using high-density surface EMG. J NeuroEng Rehabil 9:78. doi:10.1186/1743-0003-9-78
McGill KC (2002) Optimal resolution of superimposed action potentials. IEEE Trans Biomed Eng 49:640–650
McGill KC, Dorfman LJ (1984) High-resolution alignment of sampled wave-forms. IEEE Trans Biomed Eng 31:462–468
McGill KC, Lateva ZC, Marateb HR (2005) EMGLAB:an interactive EMG decomposition program. J Neurosci Methods 149(2):121–133
Kleine Bert U, van Dijk Johannes P (2007) Using two-dimensional spatial information in decomposition of surface EMG signals. J Electromyogr Kinesiol 17:535–548
Drost Gea, Kleine Bert U (2007) Fasciculation potentials in high-density surface EMG. J Clin Neurophysiol 24:301–307
Kleine Bert U, Stegeman Dick F (2008) Firing pattern of fasciculations in ALS: evidence for axonal and neuronal origin. Neurology 70:353
Zhou P, Suresh NL, Rymer WZ (2011) Surface electromyogram analysis of the direction of isometric torque generation by the first dorsal interosseous muscle. J Neural Eng 8(3):036028. Epub 13 May 2011
Rosenfeld J (2000) Fasciculations without fibrillations: the dilemma of early diagnosis. Amyotroph Lateral Scler Other Motor Neuron Disord 1(Suppl 1):S53–S56
De Carvalho M, Swash M (1998) Fasciculation potentials: a study of amyotrophic lateral sclerosis and other neurogenic disorders. Muscle Nerve 21(3):336–344
Noto YI, Misawa S, Kanai K, Shibuya K, Isose S, Nasu S, Sekiguchi Y, Fujimaki Y, Nakagawa M, Kuwabara S (2011) Awaji ALS criteria increase the diagnostic sensitivity in patients with bulbar onset. Clin Neurophysiol.122 (12) Epub ahead of print
Mills KR (2010) Characteristics of fasciculations in amyotrophic lateral sclerosis and the benign fasciculation syndrome. Brain 133(11):3458–3469. Epub Oct 2010
Acknowledgment
This study was supported by National Nature Science Foundation of China (NFSC) under Grant 81271658.
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Chen, B., Zhou, P. (2014). Detection of Fasciculation Potentials in Amyotrophic Lateral Sclerosis Using Surface EMG. In: Li, S., Jin, Q., Jiang, X., Park, J. (eds) Frontier and Future Development of Information Technology in Medicine and Education. Lecture Notes in Electrical Engineering, vol 269. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-7618-0_302
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DOI: https://doi.org/10.1007/978-94-007-7618-0_302
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