Clinical Research on Using Hepatocyte Growth-Promoting Factors Combined with Gongying Yinchen Soup to Cure Depression in Patients with Fulminant Hepatitis

  • Guo Kaoshan
  • Hou Shuying
  • Gao Junfeng
  • Zhao Xinguo
  • Li Jianqiao
  • Li Huilong
  • Hou Jinjie
  • Ma Limin
  • Li Meng
  • Sun Yanfu
  • Gu Qing
  • Li Ruiyu
Conference paper
Part of the Lecture Notes in Electrical Engineering book series (LNEE, volume 269)

Abstract

Objective Discuss the effect of using Hepatocyte growth-promoting factors combined with Gongying Yinchen soup to cure depression in patients with fulminant hepatitis. Methods Choose 61 cases of fulminant hepatitis patients with depression, With reference to the American psychiatric association Mental disorders diagnostic and statistical manual (DSM-IV) Classification standard, 31 cases patients were randomly divided into treatment group, which was given Gongying Yinchen soup and intravenous drip of 10 % glucose injection 250 ml containing Hepatocyte growth-promoting factors 120 rag, once daily, 15 days for a course of treatment and 30 in the control group, application of this method at the same time added nutgrass galingale rhizome, radix curcumae, radix angelicae sinensis, radix paeoniae alba, radix aucklandiae and other drugs. After three courses of treatment, HAMD rating scale, scores of TCM symptoms. Determine the efficacy. Results Use Gongying Yinchen soup combined with promoting liver cell growth hormone treatment of severe hepatitis patients with depression after treatment, pretherapy and post-treatment in the two groups of HAMD scale total score, treatment group before treatment 45.23 ± 17.29, after the treatment 44.25 ± 18.14; the control group before treatment 43.25 ± 18.30, after the treatment 28.46 ± 14.08, the therapeutic effect of control group patients was much better than that of treatment group cases (P < 0.05); Chinese medicine symptom curative effect as a whole,Treatment group total effectiveness 80.6 %, control group 93.3 %, had significant statistical differences were compared (P < 0.05). Conclusions Promoting liver cell growth to combination the Gongying Yinchen soup curative effect in patients with severe hepatitis depression significantly.

Keywords

Hepatocyte growth-promoting factors Gongying Yinchen soup Fulminant hepatitis Depression 

References

  1. 1.
    Wang Q (2011) 42 cases of fulminant hepatitis risk factor of prognosis analysis. Jilin Med J 32(2):233–234Google Scholar
  2. 2.
    Branch association of infectious diseases and parasitic epidemiology (2001) Branch association of Hepatology, Chinese medical association. Virus hepatitis integrated control measure. Chin J Infect Dis 19(1):56–62Google Scholar
  3. 3.
    Branch of the Chinese medical association of psychiatry (2001) The Chinese classification and diagnosis of Mental Diseases, 3rd edn (CCMD-3). Shandong Science & Technology Press, Jinan, pp 87–89Google Scholar
  4. 4.
    Chen ZQ, Hu SY, Zhang HN et al (2005) Studying on common TCM syndromes of depression. J Tradit Chin Med 46(1):47–49Google Scholar
  5. 5.
    SFDA (2002) Refer to directions of new drugs clinical research (try out). China Press of Traditional Chinese Medicine, Beijing, p 105Google Scholar
  6. 6.
    Labrecque DR (1975) Rogeneration stimulator substance (HSS) from preparation and partial characterization of hepatic rat liver. J Physiol 248(5):273Google Scholar
  7. 7.
    Michalopoulos GK, Zarnegar R (1992) Hepatocyte growth factor. Hepatology 15(1):149–155CrossRefGoogle Scholar
  8. 8.
    Kong XP, Zheng GC, Zhang YZ et al (1991) Hepatocyte stimulating factor of rat experimental liver failure factors and the experimental mechanism research. Chin J Digestion 11(1):23Google Scholar
  9. 9.
    Zhang YZ, Zheng GC, Kong XP et al (1991) J Clin Hepatol 7(1):15Google Scholar
  10. 10.
    Shi SM, Zhang X (2000) Blood transfusion or blood products infected with hepatitis c patient’s mental nursing. J Heze Med Coll 12(3):140Google Scholar
  11. 11.
    Xu B, Wang XD, Liu SL (2000) Psychosomatic medicine. China Science and Technology Press, pp 248–250Google Scholar
  12. 12.
    Sui ZQ, Xu ZG, Wang Y (2012) Depressive disorders and study on the relationship between the physical diseases. J Psychiatry 25(2):153–156Google Scholar

Copyright information

© Springer Science+Business Media Dordrecht 2014

Authors and Affiliations

  • Guo Kaoshan
    • 1
  • Hou Shuying
    • 2
  • Gao Junfeng
    • 1
  • Zhao Xinguo
    • 3
  • Li Jianqiao
    • 4
  • Li Huilong
    • 1
  • Hou Jinjie
    • 5
  • Ma Limin
    • 3
  • Li Meng
    • 6
  • Sun Yanfu
    • 1
  • Gu Qing
    • 1
  • Li Ruiyu
    • 7
  1. 1.Second Affiliated Hospital of Xing Tai Medical CollegeXingtaiChina
  2. 2.Qianjiudian Primary School of Guangzong CountyXingtaiChina
  3. 3.Chinese Medicine Hospital of Lincheng CountyHebeiChina
  4. 4.Chinese Medicine Hospital of LuquanHebeiChina
  5. 5.Xingtai Medical CollegeXingtaiChina
  6. 6.Health Team of Hotan Prefecture Detachment of Chinese Armed Police ForceXinjiangChina
  7. 7.Second Affiliated Hospital of Xing Tai Medical CollegeXingtaiChina

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