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The Influence of Hepatocyte Growth-Promoting Factors Combined with Gongying Yinchen Soup for Depression in Patients with Fulminant Hepatitis Peripheral Blood T Lymphocyte Subsets and Liver Function

  • Liping Wu
  • Junfeng Gao
  • Xinguo Zhao
  • Huilong Li
  • Jianqiao Li
  • Limin Ma
  • Meng Li
  • Weihua Han
  • Qing Gu
  • Ruiyu Li
Conference paper
Part of the Lecture Notes in Electrical Engineering book series (LNEE, volume 269)

Abstract

Objective To investigate the effect of the influence of hepatocyte growth-promoting factors combined with Gongying Yinchen soup for depression in patients with fulminant hepatitis peripheral blood T lymphocyte subsets and liver function. Methods Choose 61 cases of fulminant hepatitis patients with depression, With reference to the American psychiatric association Mental disorders diagnostic and statistical manual (DSM-IV) Classification standard, 31 cases patients were randomly divided into treatment group, which was given intravenous drip of 10 % glucose injection 250 ml containing Hepatocyte growth-promoting factors 120 rag, once daily, 15 days for a course of treatment and 30 in the control group, Application of above methods at the same time to add with the Gongying Yinchen soup, etc. (Dandelion, radix et rhizoma rhei, radix bupleuri, herba artemisiae capillaris, glabrous greenbrier rhizome, radix isatidis, grifola, bitter ginseng). After the treatment for three courses, the peripheral blood T lymphocyte subsets (by FACSCalibur flow cytometry) and liver function were detected. Results After the treatments the level of CD3+ CD4+ CD4+/CD8+ increased in two groups with more marked elevation in control group (P < 0.01); The level of CD8+ counts decreased. Compared with the treatment group, the change of control group was more significant (P < 0.05); The level of ALT AST and GGT in two groups decreased, But the control group decreased obviously (P < 0.05, P < 0.01). Conclusions Hepatocyte growth-promoting factors combined with Gongying Yinchen soup in patients with fulminant hepatitis depression can affect the peripheral blood T lymphocyte subsets, can enhance the body’s immune response ability.

Keywords

Hepatocyte growth-promoting factors Gongying Yinchen soup Fulminant hepatitis T lymphocyte subsets Liver function 

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Copyright information

© Springer Science+Business Media Dordrecht 2014

Authors and Affiliations

  • Liping Wu
    • 1
  • Junfeng Gao
    • 2
  • Xinguo Zhao
    • 3
  • Huilong Li
    • 2
  • Jianqiao Li
    • 4
  • Limin Ma
    • 3
  • Meng Li
    • 5
  • Weihua Han
    • 2
  • Qing Gu
    • 2
  • Ruiyu Li
    • 6
  1. 1.Xingtai People’s HospitalXingtaiChina
  2. 2.Second Affiliated Hospital of Xingtai Medical CollegeXingtaiChina
  3. 3.Chinese Medicine Hospital of Lincheng CountyXingtaiChina
  4. 4.Chinese Medicine HospitalLuquanChina
  5. 5.Health Team of Hotan Prefecture Detachment of Chinese Armed Police ForceXinjiangChina
  6. 6.Institute of Integrated Traditional and Western MedicineSecond Affiliated Hospital, Xingtai Medical CollegeXingtaiChina

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