Meta-Analysis of Chinese Herbs in the Treatment of Nephropathy: Huangqi and Danggui Type Formulations

  • Ming-gang wei
  • Xiao-feng Cai
Conference paper
Part of the Lecture Notes in Electrical Engineering book series (LNEE, volume 269)


Objective Numerous Chinese patients with Diabetic nephropathy (DN) have benefited from chinese herbs. However, there is no systematic evaluation about them. Methods We conducted a meta-analysis to all eligible randomized clinical trials (RCTs) to assess the effect of Chinese herbs on DN for the first time. Results (1) Five eligible RCTs with 356 participants; (2) Chinese herbs brought a favorable increase in total remission (TR) (RR2.60, 95 %CI 1.55 to4.34, I2 = 0 %) compared with non-Chinese herbs treatment; (3) Exploiting subgroup meta-analysis, Chinese herbs led to significantly improvements of DN with ACEI treatment with regard to the decrease of urinary proteinuria excretion (UPE) (MD −23.65 ug/min, 95 % CI −29.37 to −17.92, I2 = 0 %) Conclusion Chinese herbs was certainly a valuable and promising treatment remedy for DN.


Diabetic nephropathy Chinese herbs Drug therapy Meta-analysis 



The work is supported by the grant from the Natural Science Foundation of China (No. 81273723).


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Copyright information

© Springer Science+Business Media Dordrecht 2014

Authors and Affiliations

  1. 1.The First Affiliated Hospital of Soochow UniversitySuzhouChina

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