Abstract

Understanding how proteins assemble into their final shapes (or “fold”) has been a grand challenge of computational biology for decades. MSM methods have allowed, for the first time, the direct simulation of how proteins fold on the microsecond to 10’s of millisecond timescale, yielding novel insight into the process.

Keywords

Beta Sheet Markov State Model Simulate Protein Folding Slow Timescale Millisecond Timescale 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media Dordrecht 2014

Authors and Affiliations

  1. 1.Stanford UniversityStanfordUSA

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