Metastatic Oligodendroglioma: Diagnosis with Fine-Needle Aspiration Cytology

  • Bilge Can Meydan
  • İlkser Akpolat
Part of the Tumors of the Central Nervous System book series (TCNS, volume 13)


Extracranial/systemic metastasis of a primary central nervous system glial tumor is very rare, but the incidence is ever-increasing. Oligodendroglial tumors are uncommon; however, after high-grade astrocytomas, they constitute an important group of tumors which are reported to cause extracranial metastases. In the majority of literature-reported cases, the likelihood of a second primary tumor is considered as the first approach; therefore metastases are overlooked. Fine-needle aspiration cytology (FNAC) is currently accepted as a reliable, accurate, cost-effective and rapid diagnostic method for possible metastatic lesions in a patient with known primary tumor. FNAC findings of metastatic oligodendroglioma and small-round-cell tumors (SRCT) are quite similar, therefore differential diagnosis requires combination of the clinical and radiological data. In addition, application of immunochemistry and detection of 1p/19q co-deletion on cytological material confirm the diagnosis.


Glial Fibrillary Acidic Protein Oligodendroglial Tumor Extracranial Metastasis Mesenchymal Chondrosarcoma Small Cell Neuroendocrin Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media Dordrecht 2014

Authors and Affiliations

  1. 1.Department of Pathology, School of MedicineOndokuz Mayis UniversitySamsunTurkey

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