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Taraxacum officinale

  • T. K. Lim
Chapter

Scientific Name

Taraxacum officinaleG.H. Weber ex F. H. Wigg.

Synonyms

Chondrilla taraxacum (L.) Stokes, Crepis taraxacum L., Leontodon officinale (L.) F.H. Wigg., Leontodon taraxacum L., Leontodon vulgare Lam. (illeg.), Taraxacum almaatense Schischk., Taraxacum laeticolor Dahlst., Taraxacum officinale var. glabratus Kirk, Taraxacum officinale var.pygmaea Hook.f., Taraxacum retroflexum H. Lindb. Taraxacum sylvanicum R. Doll, Taraxacum taraxacum (L.) H. Karst., nom. inval., tautonym

Family

Asteraceae

Common/English Names

Blowball, Broad-Lobed Dandelion, Cankerwort, Common Dandelion, Dandelion, Faceclock, Fairy Clock, Irish Daisy, Lion’s-Tooth, Milk Gowan, Pissabed, Priest’s Crown, Puffball, Swine’s Snout, Telltime, Wet-A-Bed, Wild Endive

Vernacular Names

  • Albanian: Luleshurdha

  • Brazil: Dente De Leão, Taraxaco

  • Chinese: Pu Cong Ying Yao Pu Cong Ying

  • Czech: Pampeliška Lékařská, Smetánka Lékařská

  • Danish: Almindelig Mælkebøtte, Fandens Mælkebøtte, Løvetand, Mælkebøtte, Mølkebøtte

  • Dutch:...

Keywords

Chlorogenic Acid Ursolic Acid Sesquiterpene Lactone Ethyl Acetate Fraction Hydroalcoholic Extract 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Selected References

  1. Akashi T, Furuno T, Takahashi T, Ayabe SI (1994) Biosynthesis of triterpenoids in cultured cells, and regenerated and wild plant organs of Taraxacum officinale. Phytochemistry 36(2):303–308Google Scholar
  2. Akashi T, Saito N, Hirota H, Ayabe S (1997) Anthocyanin-producing dandelion callus as a chalcone synthase source in recombinant polyketide reductase assay. Phytochemistry 46(2):283–287PubMedGoogle Scholar
  3. Akhtar MS, Khan QM, Khaliq T (1985) Effects of Portulaca oleracea (Kulfa) and Taraxacum officinale (Dhudhal) in normoglycaemic and alloxan-treated hyperglycaemic rabbits. J Pak Med Assoc 35(7):207–210PubMedGoogle Scholar
  4. Astafieva AA, Rogozhin EA, Odintsova TI, Khadeeva NV, Grishin EV, Egorov TA (2012) Discovery of novel antimicrobial peptides with unusual cysteine motifs in dandelion Taraxacum officinale Wigg. Flowers. Peptides 36(2):266–271Google Scholar
  5. Baba K, Abe S, Mizuno D (1981) Antitumor activity of hot water extract of dandelion, Taraxacum officinale—correlation between antitumor activity and timing of administration. Yakugaku Zasshi 101(6):538–543 (In Japanese)PubMedGoogle Scholar
  6. Bacon JSD, Eldeman J (1951) The carbohydrates of the Jerusalem artichoke and other Compositae. Biochem J 48:114–126PubMedCentralPubMedGoogle Scholar
  7. Blumenthal M, Busse WR, Goldberg A, Gruenwald J, Hall T, Riggins CW, Rister RS (eds) (1998) The complete German Commission E monographs: therapeutic guide to herbal medicines. American Botanical Council, Integrative Medicine Communications, Austin, 685 ppGoogle Scholar
  8. Bogacheva AM, Rudenskaya GN, Preusser A, Tchikileva IO, Dunaevsky YE, Golovkin BN, Stepanov VM (1999) A new subtilisin-like proteinase from roots of the dandelion Taraxacum officinale Webb S. L. Biochemistry (Mosc) 64(9):1030–1037Google Scholar
  9. Booth VH (1964) Taraxien, the carotenoid ester in dandelion flowers. Phytochemistry 3(2):229–234Google Scholar
  10. Bown D (1995) Encyclopaedia of herbs and their uses. Dorling Kindersley, London, 424 ppGoogle Scholar
  11. Budzianowski J (1997) Coumarins, caffeoyltartaric acids and their artifactual methyl esters from Taraxacum officinale leaves. Planta Med 63:288PubMedGoogle Scholar
  12. Cadosh H, Voegeli U, Ruedi P, Eugster CH (1978) Flavoxanthin and chrysanthemaxanthin carotenoids: proton NMR, carbon-13 NMR, mass spectra and absolute configuration. Critical survey of published chemical and physical data. Helv Chim Acta 61(2):783–794Google Scholar
  13. Causey JL, Feirtag JM, Gallaher DD, Tungland BC, Slavin JL (2000) Effects of dietary inulin on serum lipids, blood glucose and the gastrointestinal environment in hypercholesterolemic men. Nutr Res 20(2):191–201Google Scholar
  14. Chakŭrski I, Matev M, Koĭchev A, Angelova I, Stefanov G (1981) Treatment of chronic colitis with an herbal combination of Taraxacum officinale, Hipericum perforatum, Melissa officinaliss, Calendula officinalis and Foeniculum vulgare. Vutr Boles 20(6):51–54 (In Bulgarian)PubMedGoogle Scholar
  15. Chiej R (1984) Encyclopaedia of medicinal plants. MacDonald, London, 447 ppGoogle Scholar
  16. Chkhikvishvili ID, Kharebava GI (2001) Chicoric and chlorogenic acids in various plants growing in Georgia. Prikl Biokhim Mikrobiol 37(2):214–217 (In Russian)PubMedGoogle Scholar
  17. Choi UK, Lee OH, Yim JH, Cho CW, Rhee YK, Lim SI, Kim YC (2010) Hypolipidemic and antioxidant effects of dandelion (Taraxacum officinale) root and leaf on cholesterol-fed rabbits. Int J Mol Sci 11(1):67–78PubMedCentralPubMedGoogle Scholar
  18. Chuakul W (1999) Taraxacum officinale Weber ex F.H. Wigg. In: de Padua LS, Bunyapraphatsara N, Lemmens RHMJ (eds) Plant resources of South-East Asia no. 12(1). Medicinal and poisonous plants 1. Prosea Foundation, Bogor, pp 475–479Google Scholar
  19. Clare BA, Conroy RS, Spelman K (2009) The diuretic effect in human subjects of an extract of Taraxacum officinale folium over a single day. J Altern Complement Med 15(8):929–934PubMedCentralPubMedGoogle Scholar
  20. Colle D, Arantes LP, Gubert P, da Luz SC, Athayde ML, Teixeira Rocha JB, Soares FA (2012a) Antioxidant properties of Taraxacum officinale leaf extract are involved in the protective effect against hepatoxicity induced by acetaminophen in mice. J Med Food 15(6):549–556PubMedGoogle Scholar
  21. Colle D, Arantes LP, Rauber R, de Mattos SE, Rocha JB, Nogueira CW, Soares FA (2012b) Antioxidant properties of Taraxacum officinale fruit extract are involved in the protective effect against cellular death induced by sodium nitroprusside in brain of rats. Pharm Biol 50(7):883–891PubMedGoogle Scholar
  22. Cordatos E (1999) Taraxacum officinale. In: Pizzorno J, Murray M (eds) A textbook of natural medicine, 2nd edn. Churchill Livingstone, Edinburgh, 1766 ppGoogle Scholar
  23. Crowe A (1990) Native edible plants of New Zealand. Hodder and Stoughton, Auckland, 184 ppGoogle Scholar
  24. Djingova R, Kuleff I, Penev I, Sansoni B (1986) Bromine, copper, manganese and lead content of the leaves of Taraxacum officinale (dandelion). Sci Total Environ 50:197–208Google Scholar
  25. Domitrović R, Jakovac H, Romić Z, Rahelić D, Tadić Z (2010) Antifibrotic activity of Taraxacum officinale root in carbon tetrachloride-induced liver damage in mice. J Ethnopharmacol 130(3):569–577PubMedGoogle Scholar
  26. Duke JA (1992) Handbook of phytochemical constituents of GRAS herbs and other economic plants. CRC Press, Boca Raton, 654 ppGoogle Scholar
  27. Duke JA (2005) Dr. Duke’s phytochemical and ethnobotanical databases. www.ars-grin.gov/duke. Accessed Apr 2012
  28. European Medicines Agency (2009) Assessment report on Taraxacum officinale Weber ex Wigg., radix cum herba. Committee on Herbal Medicinal Products (European Medicines Agency), London, 19 ppGoogle Scholar
  29. Facciola S (1990) Cornucopia. A source book of edible plants. Kampong Publications, Vista, 677 ppGoogle Scholar
  30. Flann C (ed) (2009+) Global compositae checklist. Accessed 1 Nov 2012Google Scholar
  31. Foster S, Duke JA (1998) A field guide to medicinal plants in eastern and central N America. Houghton Mifflin, Boston, 366 ppGoogle Scholar
  32. Fraisse D, Felgines C, Texier O, Lamison J-L (2011) Caffeoyl derivatives: major antioxidant compounds of some wild herbs of the Asteraceae family. Food Nutr Sci 2:181–192Google Scholar
  33. Gargouri M, Ghorbel-Koubaa F, Bonenfant-Magné M, Magné C, Dauvergne X, Ksouri R, Krichen Y, Abdelly C, El Feki A (2012) Spirulina or dandelion-enriched diet of mothers alleviates lead-induced damages in brain and cerebellum of newborn rats. Food Chem Toxicol 50(7):2303–2310PubMedGoogle Scholar
  34. Goksu E, Eken C, Karadeniz O, Kucukyilmaz O (2010) First report of hypoglycemia secondary to dandelion (Taraxacum officinale) ingestion. Am J Emerg Med 28(1):111.e1–111.e2Google Scholar
  35. Grases F, Melero G, Costa-Bauzá A, Prieto R, March JG (1994) Urolithiasis and phytotherapy. Int Urol Nephrol 26(5):507–511PubMedGoogle Scholar
  36. Greenlee H, Atkinson C, Stanczyk FZ, Lampe JW (2007) A pilot and feasibility study on the effects of naturopathic botanical and dietary interventions on sex steroid hormone metabolism in premenopausal women. Cancer Epidemiol Biomarkers Prev 16(8):1601–1609PubMedGoogle Scholar
  37. Grieve M (1971) A modern herbal, 2 vols. Penguin/Dover publications, New York, 919 ppGoogle Scholar
  38. Guin JD, Skidmore G (1987) Compositae dermatitis in childhood. Arch Dermatol 123(4):500–502PubMedGoogle Scholar
  39. Hagymási K, Blázovics A, Fehér J, Lugasi A, Kristó ST, Kéry A (2000) The in vitro effect of dandelion’s antioxidants on the microsomal lipid peroxidation. Phytother Res 14(1):43–44PubMedGoogle Scholar
  40. Halpin AM (1978) Unusual vegetables: something new for this year’s garden. Rodale Press, Emmaus, 443 ppGoogle Scholar
  41. Han H, He W, Wang W, Gao B (2011) Inhibitory effect of aqueous dandelion extract on HIV-1 replication and reverse transcriptase activity. BMC Complement Altern Med 11:112PubMedCentralPubMedGoogle Scholar
  42. Hanawa F, Kanauchi M, Tahara S, Mizutani J (1995) Lettucenin a as a phytoalexin of dandelion and its elicitation in dandelion cell cultures. J Fac Agric Hokkaido Univ 66(2):151–152Google Scholar
  43. Hannemann K, Puchta V, Simon E, Ziegler H, Ziegler G, Spiteller G (1998) The common occurrence of furan fatty acids in plants. Lipids 24(4):296–298Google Scholar
  44. Hansel R, Kartarahardja M, Huang JT, Bohlmann F (1980) A sesquiterpene lactone-beta-d-glucopyranoside and a new eudesmanolide from Taraxacum officinale. Phytochemistry 19(5):857–861Google Scholar
  45. Harrington HD (1974) Edible native plants of the rocky mountains. University New Mexico Press, Albuquerque, 392 ppGoogle Scholar
  46. Hatfield AW (1977) How to enjoy your weeds. Frederick Muller Ltd., London, 116 ppGoogle Scholar
  47. Hirono I, Mori H, Kato K, Ushimaru Y, Kato T, Haga M (1978) Safety examination of some edible plants, part 2. J Environ Pathol Toxicol 1(1):71–74PubMedGoogle Scholar
  48. Hoagland RE (1975) Hydrolysis of 3′,4′-dichloropropionanilide by an aryl acylamidase from Taraxacum officinale. Phytochemistry 14(2):383–386Google Scholar
  49. Hook I, Sheridan H, Wilson G (1991) Volatile metabolites from suspension cultures of Taraxacum officinale. Phytochemistry 30:3977–3979Google Scholar
  50. Hu C, Kitts DD (2003) Antioxidant, prooxidant, and cytotoxic activities of solvent-fractionated dandelion (Taraxacum officinale) flower extracts in vitro. J Agric Food Chem 51(1):301–310PubMedGoogle Scholar
  51. Hu C, Kitts DD (2004) Luteolin and luteolin-7-O-glucoside from dandelion flower suppress iNOS and COX-2 in RAW264.7 cells. Mol Cell Biochem 265(1–2):107–113Google Scholar
  52. Hu C, Kitts DD (2005) Dandelion (Taraxacum officinale) flower extract suppresses both reactive oxygen species and nitric oxide and prevents lipid oxidation in vitro. Phytomedicine 12(8):588–597PubMedGoogle Scholar
  53. Hussain Z, Waheed A, Qureshi RA, Burdi DK, Verspohl EJ, Khan N, Hasan M (2004) The effect of medicinal plants of Islamabad and Murree region of Pakistan on insulin secretion from INS-1 cells. Phytother Res 18(1):73–77PubMedGoogle Scholar
  54. Jeon HJ, Kang HJ, Jung HJ, Kang YS, Lim CJ, Kim YM, Park EH (2008) Anti-inflammatory activity of Taraxacum officinale. J Ethnopharmacol 115(1):82–88PubMedGoogle Scholar
  55. Jin YR, Jin J, Piao XX, Jin NG (2011) The effect of Taraxacum officinale on gastric emptying and smooth muscle motility in rodents. Neurogastroenterol Motil 23(8):766–e333PubMedGoogle Scholar
  56. Kang JW, Kim SJ, Kim HY, Cho SH, Kim KN, Lee SG, Lee SM (2012) Protective effects of HV-P411 complex against d-galactosamine-induced hepatotoxicity in rats. Am J Chin Med 40(3):467–480PubMedGoogle Scholar
  57. Kango N (2008) Production of inulinase using tap roots of dandelion (Taraxacum officinale) by Aspergillus niger. J Food Eng 85(3):473–478Google Scholar
  58. Kashiwada Y, Takanaka K, Tsukada H, Miwa Y, Taga T, Tanaka S (2001) Sesquiterpene glucosides from anti-leukotriene B4 release fraction of Taraxacum officinale. J Asian Nat Prod Res 3(3):191–197PubMedGoogle Scholar
  59. Kim HM, Oh CH, Chung CK (1999) Activation of inducible nitric oxide synthase by Taraxacum officinale in mouse peritoneal macrophages. Gen Pharmacol 32(6):683–688PubMedGoogle Scholar
  60. Kim HM, Shin HY, Lim KH, Ryu ST, Shin TY, Chae HJ, Kim HR, Lyu YS, An NH, Lim KS (2000) Taraxacum officinale inhibits tumor necrosis factor-alpha production from rat astrocytes. Immunopharmacol Immunotoxicol 22(3):519–530PubMedGoogle Scholar
  61. Kisiel W, Barszcz B (2000) Further sesquiterpenoids and phenolics from Taraxacum officinale. Fitoterapia 71(3):269–273PubMedGoogle Scholar
  62. Kisiel W, Barszcz B, Szneler E (2000) A new lupine-type triterpenoid from Taraxacum officinale. Pol J Chem 74(2):281–283Google Scholar
  63. Koh YJ, Cha DS, Ko JS, Park HJ, Choi HD (2010) Anti-inflammatory effect of Taraxacum officinale leaves on lipopolysaccharide-induced inflammatory responses in RAW 264.7 cells. J Med Food 13(4):870–878PubMedGoogle Scholar
  64. Komine H, Takahashi T, Ayabe S-I (1996) Properties and partial purification of squalene synthase from cultured cells of dandelion. Phytochemistry 42(2):405–409Google Scholar
  65. Komissarenco NF, Derkach AI (1982) Taraxacum officinale coumarins. Khim Prir Soedin 4:519, Chem Abstr 96:3647Google Scholar
  66. Koo HN, Hong SH, Song BK, Kim CH, Yoo YH, Kim HM (2004) Taraxacum officinale induces cytotoxicity through TNF-alpha and IL-1alpha secretion in Hep G2 cells. Life Sci 74(9):1149–1157PubMedGoogle Scholar
  67. Kristó TS, Szőke É, Terdy AKPP, Selmeczi LK, Simándi B (2003) Production and characterisation of Taraxacum officinale extracts prepared by supercritical fluid and solvent extractions. Acta Hortic 597:57–61Google Scholar
  68. Kuusi T, Pyylaso H, Autio K (1985) The bitterness properties of dandelion. II. Chemical investigations. Lebensm Wiss Technol 18:347–349Google Scholar
  69. Lee YW, Choi SY, Lee EK, Sohn JH, Park JW, Hong CS (2007) Cross-allergenicity of pollens from the Compositae family: Artemisia vulgaris, Dendranthema grandiflorum, and Taraxacum officinale. Ann Allergy Asthma Immunol 99(6):516–533Google Scholar
  70. Lee BR, Lee JH, An HJ (2012) Effects of Taraxacum officinale on fatigue and immunological parameters in mice. Molecules 17(11):13253–13265PubMedGoogle Scholar
  71. Liu L, Xiong H, Ping J, Ju Y, Zhang X (2010) Taraxacum officinale protects against lipopolysaccharide-induced acute lung injury in mice. J Ethnopharmacol 130(2):392–397PubMedGoogle Scholar
  72. Lust JB (1974) The herb book. Bantam Books, New York, p 174Google Scholar
  73. MacNicol M (1967) Flower cookery. Fleet Press, New YorkGoogle Scholar
  74. Mahesh A, Jeyachandran R, Cindrella L, Thangadurai D, Veerapur VP, Muralidhara Rao D (2010) Hepatocurative potential of sesquiterpene lactones of Taraxacum officinale on carbon tetrachloride induced liver toxicity in mice. Acta Biol Hung 61(2):175–190PubMedGoogle Scholar
  75. Masaaki S, Eriko D, Riyo Y, Takehiko T, Yutaka E (2006) Biosynthesis of triterpenes in Taraxacum officinale. J Pharm Soc Jpn 126(5):200–203Google Scholar
  76. Meléndez-Martínez AJ, Britton G, Vicario IM, Heredia FJ (2006) HPLC analysis of geometrical isomers of lutein epoxide isolated from dandelion (Taraxacum officinale F. Weber ex Wiggers). Phytochemistry 67(8):771–777PubMedGoogle Scholar
  77. Mizushina Y, Yoshida H, Matsumoto H, Iida A (2003) Cyanogenic glycoside from Taraxacum officinale. Nat Med 57(1):36Google Scholar
  78. Modaresi M, Resalatpour N (2012) The effect of Taraxacum officinale hydroalcoholic extract on blood cells in mice. Adv Hematol 2012:653412PubMedCentralPubMedGoogle Scholar
  79. Odintsova TI, Rogozhin EA, Sklyar IV, Musolyamov AK, Kudryavtsev AM, Pukhalsky VA, Smirnov AN, Grishin EV, Egorov TA (2010) Antifungal activity of storage 2S albumins from seeds of the invasive weed dandelion Taraxacum officinale Wigg. Protein Pept Lett 17(4):522–529PubMedGoogle Scholar
  80. Olennikov DN, Tankhaeva LM, Rokhin AV (2009) Glucofructans from Taraxacum officinale roots. Chem Nat Compd 45(2):141–144Google Scholar
  81. Ovadje P, Chatterjee S, Griffin C, Tran C, Hamm C, Pandey S (2011) Selective induction of apoptosis through activation of caspase-8 in human leukemia cells (Jurkat) by dandelion root extract. J Ethnopharmacol 133(1):86–91PubMedGoogle Scholar
  82. Park CM, Youn HJ, Chang HK, Song YS (2010) TOP1 and 2, polysaccharides from Taraxacum officinale, attenuate CCl(4)-induced hepatic damage through the modulation of NF-kappaB and its regulatory mediators. Food Chem Toxicol 48(5):1255–1261PubMedGoogle Scholar
  83. Park CM, Jin KS, Lee YW, Song YS (2011a) Luteolin and chicoric acid synergistically inhibited inflammatory responses via inactivation of PI3K-Akt pathway and impairment of NF-κB translocation in LPS stimulated RAW 264.7 cells. Eur J Pharmacol 660(2–3):454–459PubMedGoogle Scholar
  84. Park CM, Park JY, Noh KH, Shin JH, Song YS (2011b) Taraxacum officinale Weber extracts inhibit LPS-induced oxidative stress and nitric oxide production via the NF-κB modulation in RAW 264.7 cells. J Ethnopharmacol 133(2):834–842PubMedGoogle Scholar
  85. Pedneault K, Léonhart S, Gosselin A, Papadopoulos AP, Dorais M, Angers P (2002) Variations in concentration of active compounds in four hydroponically-and field-grown medicinal plant species. Acta Hortic (ISHS) 580:255–262Google Scholar
  86. Petlevski R, Hadzija M, Slijepcevic M, Juretic D (2001) Effect of ‘antidiabetis’ herbal preparation on serum glucose and fructosamine in NOD mice. J Ethnopharmacol 75(2–3):181–184Google Scholar
  87. Rácz-Kotilla E, Rácz G, Solomon A (1974) The action of Taraxacum officinale extracts on the body weight and diuresis of laboratory animals. Planta Med 26:212–217PubMedGoogle Scholar
  88. Ragasa CY, Apuada MJ, Rideout JA (2009) Terpenoids from Taraxacum officinale. NCRP Res J 10(1):17–26Google Scholar
  89. Rauwald HW, Huang JT (1985) Taraxacoside, a type of acylated gammabutyrolactone glycoside from Taraxacum officinale. Phytochemistry 24(7):1557–1559Google Scholar
  90. Richards AJ (1973) The origin of Taraxacum agamospecies. Bot J Linn Soc 66:189–211Google Scholar
  91. Richards AJ (1985) Sectional nomenclature in Taraxacum (Asteraceae). Taxon 34:633–644Google Scholar
  92. Roberts MJ (2000) Edible & medicinal flowers. New Africa Publishers, Claremont, 160 ppGoogle Scholar
  93. Rudenskaya GN, Bogacheva AM, Preusser A, Kuznetsova AV, Dunaevsky YE, Golovkin BN, Stepanov VM (1998) Taraxalisin – a serine proteinase from dandelion Taraxacum officinale Webb s.l. FEBS Lett 437(3):237–240Google Scholar
  94. Rutherford PP, Deacon AC (1972) ß-Fructofurasonidase from roots of dandelion (Taraxacum officinale Weber). Biochem J 126:569–573PubMedCentralPubMedGoogle Scholar
  95. Saeki D, Yamada T, In Y, Kajimoto T, Tanaka R, Iizuka Y, Nakane T, Takano A, Masuda K (2013) Officinatrione: an unusual (17S)-17,18-seco-lupane skeleton, and four novel lupane-type triterpenoids from the roots of Taraxacum officinale. Tetrahedron 69(5):1583–1589Google Scholar
  96. Schütz K, Kammerer DR, Carle R, Schieber A (2005) Characterization of phenolic acids and flavonoids in dandelion (Taraxacum officinale WEB. ex WIGG.) root and herb by high-performance liquid chromatography/electrospray ionization mass spectrometry. Rapid Commun Mass Spectrom 19(2):179–186PubMedGoogle Scholar
  97. Schütz K, Carle R, Schieber A (2006a) Taraxacum – a review on its phytochemical and pharmacological profile. J Ethnopharmacol 107(3):313–323PubMedGoogle Scholar
  98. Schütz K, Muks E, Carle R, Schieber A (2006b) Separation and quantification of inulin in selected artichoke (Cynara scolymus L.) cultivars and dandelion (Taraxacum officinale WEB. ex WIGG.) roots by high-performance anion exchange chromatography with pulsed amperometric detection. Biomed Chromatogr 20:1295–1303PubMedGoogle Scholar
  99. Seo SW, Koo HN, An HJ, Kwon KB, Lim BC, Seo EA, Ryu DG, Moon G, Kim HY, Kim HM, Hong SH (2005) Taraxacum officinale protects against cholecystokinin-induced acute pancreatitis in rats. World J Gastroenterol 11(4):597–599PubMedGoogle Scholar
  100. Sharafzadeh S (2011) Pyrethrum, coltsfoot and dandelion: Important medicinal plants from Asteraceaae family. Aust J Basic Appl Sci 5(12):1787–1791Google Scholar
  101. Sigstedt SC, Hooten CJ, Callewaert MC, Jenkins AR, Romero AE, Pullin MJ, Kornienko A, Lowrey TK, Slambrouck SV, Steelan WF (2008) Evaluation of aqueous extracts of Taraxacum officinale on growth and invasion of breast and prostate cancer cells. Int J Oncol 32(5):1085–1090PubMedGoogle Scholar
  102. Simándi B, Kristo ST, Kéry Á, Selmeczi LK, Kmecz I, Kemény S (2002) Supercritical fluid extraction of dandelion leaves. J Supercrit Fluid 23(2):135–142Google Scholar
  103. Sumanth M, Rana A (2006) In vivo antioxidant activity of hydro-alcoholic extract of Taraxacum officinale roots in rats. Indian J Pharmacol 38(1):54–55Google Scholar
  104. Swanston-Flatt SK, Day C, Flatt PR, Gould BJ, Bailey CJ (1998) Glycaemic effects of traditional European plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetes Res 10(2):69–73Google Scholar
  105. Tahara S, Hanawa F, Harda Y, Mizutani J (1988) A fungitoxin inducibly produced by dandelion leaves treated with cupric chloride. Agric Biol Chem 52(11):2947–2948Google Scholar
  106. Tahtamouni LH, Alqurna NM, Al-Hudhud MY, Al-Hajj HA (2011) Dandelion (Taraxacum officinale) decreases male rat fertility in vivo. J Ethnopharmacol 135(1):102–109PubMedGoogle Scholar
  107. Tanaka Y, Nguyen VK (2007) Edible wild plants of Vietnam—the bountiful garden. Orchid Press, Bangkok, 175 ppGoogle Scholar
  108. Trojanová I, Rada V, Kokoska L, Vlková E (2004) The bifidogenic effect of Taraxacum officinale root. Fitoterapia 75(7–8):760–763PubMedGoogle Scholar
  109. U.S. Department of Agriculture, Agricultural Research Service (2012) USDA national nutrient database for standard reference, release 24. Nutrient Data Laboratory Home Page. http://www.ars.usda.gov/ba/bhnrc/ndl
  110. US Food and Drug Administration (US FDA) (2012) Code of federal regulations title 21. http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?fr=182.20
  111. Van Loo J, Coussement P, De Leenheer L, Hoebregs H, Smits G (1995) The presence of inulin and oligofructose as natural ingredients in western diet. CRC Crit Rev Food Sci Nutr 35:525–552Google Scholar
  112. Vogel G (1977) Natural substances with effects on the liver. In: Wagner H, Wolff P (eds) New natural products and plant drugs with pharmacological, biological or therapeutic activity. Springer, HeidelbergGoogle Scholar
  113. Westerman L, Roddick JG (1981) Annual variation in sterol levels in leaves of Taraxacum officinale Weber. Plant Physiol 68:872–875PubMedCentralPubMedGoogle Scholar
  114. Williams CA, Goldstone F, Greenham J (1996) Flavonoids, cinnamic acids and coumarins from the different tissues and medicinal preparations of Taraxacum officinale. Phytochemistry 42(1):121–127PubMedGoogle Scholar
  115. Xu XY, Butler SM, Greenwood JS, Bewley JD (2000) Stress-mediated effects on the expression of a predominant 18-kDa Taraxacum officinale root protein. Plant Physiol Biochem 39(6):491–497Google Scholar
  116. Yarnell E, Abascal K (2009) Dandelion (Taraxacum officinale and T. mongolicum). Integr Med 8(2):35–38Google Scholar
  117. Yasukawa K, Akihisa T, Inoue Y, Tamura T, Yamanouchi S, Takido M (1998) Inhibitory effect of the methanol extracts from compositae plants on 12-O-tetradecanoylphorbol-13-acetate-induced ear oedema in mice. Phytother Res 12(7):484–487Google Scholar
  118. You YH, Yoo SN, Yoon HG, Park JJ, Lee YH, Kim SO, Oh KT, Lee JM, Cho HY, Jun WJ (2010) In vitro and in vivo hepatoprotective effects of the aqueous extract from Taraxacum officinale (dandelion) root against alcohol-induced oxidative stress. Food Chem Toxicol 48(6):1632–1637PubMedGoogle Scholar
  119. Zhang JC, Chen J (2011) The effects of Taraxacum officinale extracts (TOE) supplementation on physical fatigue in mice. Afr J Tradit Complement Altern Med 8(2):128–133Google Scholar
  120. Zhang J, Kang MJ, Kim MJ, Kim ME, Song JH, Lee YM, Kim JI (2008) Pancreatic lipase inhibitory activity of Taraxacum officinale in vitro and in vivo. Nutr Res Pract 2(4):200–203PubMedCentralPubMedGoogle Scholar
  121. Zhang X, Xiong H, Liu L (2012) Effects of taraxasterol on inflammatory responses in lipopolysaccharide-induced RAW 264.7 macrophages. J Ethnopharmacol 141(1):206–211PubMedGoogle Scholar
  122. Zhi X, Honda K, Ozaki K, Misugi T, Sumi T, Ishiko O (2007) Dandelion T-1 extract up-regulates reproductive hormone receptor expression in mice. Int J Mol Med 20(3):287–292PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media Dordrecht 2014

Authors and Affiliations

  • T. K. Lim
    • 1
  1. 1.CanberraAustralia

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